The Science Behind (2R)-2-Aminoadipic Acid: Purity, Synthesis, and Applications
In the realm of fine chemicals and pharmaceutical intermediates, a deep understanding of a compound's scientific properties is crucial for effective utilization. This article delves into the specifics of (2R)-2-Aminoadipic Acid (CAS 7620-28-2), exploring its molecular characteristics, synthesis considerations, and the breadth of its applications in pharmaceutical development and biochemical research. We also touch upon the importance of sourcing from expert manufacturers, particularly within China's advanced chemical industry.
Molecular Profile and Physical Properties
(2R)-2-Aminoadipic Acid, with the molecular formula C6H11NO4 and a molecular weight of 161.1558 g/mol, is a specific stereoisomer of 2-aminoadipic acid. Its IUPAC name is (2R)-2-aminohexanedioic acid. The compound is typically characterized by its appearance as a white crystalline powder. For chemical synthesis and formulation, its solubility in water is a key attribute, facilitating its integration into aqueous reaction mixtures and solutions. The compound's chiral nature, specifically the R-configuration at the alpha-carbon, is central to its value in stereoselective synthesis.
Synthesis Considerations and Quality Control
The synthesis of enantiomerically pure compounds like (2R)-2-Aminoadipic Acid requires precise control over reaction conditions and often involves stereoselective synthesis techniques. Achieving a high purity level, typically ≥99%, is paramount, especially for pharmaceutical applications. Manufacturers must implement robust quality control measures throughout the production process, from raw material sourcing to final product analysis. Techniques such as High-Performance Liquid Chromatography (HPLC) and Nuclear Magnetic Resonance (NMR) spectroscopy are essential for verifying purity and stereochemical integrity. Certificates of Analysis (CoAs) are indispensable documentation, providing purchasers with detailed information on the product's specifications and test results.
Diverse Applications Across Industries
The unique chemical structure and chirality of (2R)-2-Aminoadipic Acid lend themselves to several critical applications:
- Pharmaceutical Intermediates: It serves as a vital chiral building block for the synthesis of Active Pharmaceutical Ingredients (APIs). Its incorporation into drug molecules can influence their efficacy, metabolic pathways, and side-effect profiles.
- Biochemical Research: Researchers utilize this compound to investigate biological pathways, study enzyme kinetics (e.g., as a potential inhibitor), and develop novel therapeutic agents.
- Peptide Synthesis: As an amino acid derivative, it can be incorporated into peptides to modify their properties or to create non-natural peptide analogs.
For R&D scientists and procurement managers, understanding these applications helps in identifying the exact intermediate needed for their specific project requirements. The ability to buy this compound from reliable sources ensures the integrity of experimental results and the efficiency of manufacturing processes.
The Role of China-Based Suppliers
China has emerged as a global leader in the production of fine chemicals and pharmaceutical intermediates. Manufacturers in China possess the expertise and infrastructure to produce compounds like (2R)-2-Aminoadipic Acid with high purity and at competitive prices. Collaborating with these suppliers provides access to advanced synthesis capabilities and a stable supply chain. We, as a dedicated chemical supplier, offer (2R)-2-Aminoadipic Acid, meeting rigorous quality standards. We invite you to request a quote and sample to evaluate our scientific expertise and commitment to product quality.
Perspectives & Insights
Core Pioneer 24
“The compound is typically characterized by its appearance as a white crystalline powder.”
Silicon Explorer X
“For chemical synthesis and formulation, its solubility in water is a key attribute, facilitating its integration into aqueous reaction mixtures and solutions.”
Quantum Catalyst AI
“The compound's chiral nature, specifically the R-configuration at the alpha-carbon, is central to its value in stereoselective synthesis.”