For chemists, researchers, and procurement specialists in the chemical and pharmaceutical industries, a deep understanding of a compound's scientific underpinnings is crucial. 4,4-Difluorocyclohexanecarboxylic Acid (CAS 122665-97-8) is a prime example of a specialized organic molecule whose unique structure dictates its valuable applications. As a leading provider of such fine chemical intermediates, we believe in illuminating the science behind our products.

Molecular Structure and Composition

The chemical identity of 4,4-Difluorocyclohexanecarboxylic Acid is precisely defined by its molecular formula: C7H10F2O2. This indicates that each molecule consists of seven carbon atoms, ten hydrogen atoms, two fluorine atoms, and two oxygen atoms. The molecular weight is approximately 164.15 g/mol. The structure features a saturated six-membered carbon ring (cyclohexane) with two fluorine atoms attached to the same carbon atom (the fourth carbon from the carboxylic acid group, following IUPAC numbering). A carboxylic acid group (-COOH) is attached to another carbon atom on the ring.

The IUPAC name, 4,4-difluorocyclohexane-1-carboxylic acid, clearly describes this arrangement. Synonyms such as '4,4-difluorocyclohexane-1-carboxylic acid', 'Maraviroc Intermediate 1', and '1-Carboxy-4,4-difluorocyclohexane' further elaborate on its structural features or specific roles in synthesis, as seen in its use as an intermediate in the synthesis of Maraviroc, an HIV medication.

Key Physical and Chemical Properties

Understanding the physical and chemical properties is essential for handling, storage, and application:

  • Appearance: Typically described as a 'White Powder' or 'White Solid', indicating its physical state at room temperature.
  • Purity: Commonly available at a high purity level, such as '99%' or '≥99.00%', which is critical for sensitive chemical reactions and pharmaceutical applications.
  • Melting Point: Reported as 103-107 °C. This range provides a clear indicator of its solid form and thermal behavior.
  • Boiling Point: Approximately 241.1 °C at 760 mmHg. This high boiling point suggests relative thermal stability.
  • Density: Around 1.24 g/cm³. This provides information on its mass per unit volume.
  • Solubility: While not always detailed, compounds of this nature are often soluble in organic solvents like chloroform and methanol.

The Significance of Fluorination

The presence of fluorine atoms in the molecule is a defining characteristic. The carbon-fluorine bond is exceptionally strong, contributing to enhanced chemical and thermal stability. Furthermore, fluorine's high electronegativity can significantly influence the electronic distribution within the molecule, affecting its reactivity and interactions with biological targets. This makes fluorinated compounds like 4,4-Difluorocyclohexanecarboxylic Acid highly sought after as intermediates for developing pharmaceuticals, agrochemicals, and advanced materials where specific properties are desired.

When you seek a 'manufacturer and supplier' for this compound, inquiring about these scientific details ensures you are obtaining a product that meets your exact specifications. As a dedicated provider, we ensure that our 4,4-Difluorocyclohexanecarboxylic Acid (CAS 122665-97-8) is supplied with comprehensive technical data to support your research and development efforts.