The intricate mechanisms governing cellular energy production are a cornerstone of biochemical research. Among the tools available to scientists exploring these processes is Atractyligenin (CAS 10391-47-6), a naturally occurring diterpene that plays a specific and vital role in modulating mitochondrial function. Understanding its action and securing a reliable supply from a trusted chemical manufacturer is key for researchers worldwide.

Atractyligenin: A Diterpene with a Precise Mechanism

Atractyligenin, with the chemical formula C19H28O4, is classified as a diterpene. Its significance in the scientific community stems from its well-documented activity as an inhibitor of mitochondrial adenine-nucleotide-translocase (ANT). ANT is a critical protein complex located in the inner mitochondrial membrane. It is responsible for the electroneutral exchange of ADP (adenosine diphosphate) from the cytosol for ATP (adenosine triphosphate) from the mitochondrial matrix. This transport is fundamental for exporting the energy currency of the cell, ATP, to fuel cellular processes.

By blocking the action of ANT, Atractyligenin directly interferes with ATP export from the mitochondria. This leads to a buildup of ATP within the mitochondrial matrix and a deficit in the cytoplasm, thereby significantly impacting cellular energy homeostasis. Researchers utilize Atractyligenin to:

  • Study the kinetics and regulation of ANT.
  • Investigate the downstream effects of altered ATP/ADP ratios in various cellular functions.
  • Explore therapeutic targets related to mitochondrial dysfunction and energy metabolism disorders.

Sourcing Quality Atractyligenin (CAS 10391-47-6)

For robust and reliable research outcomes, it is imperative to buy Atractyligenin from suppliers who guarantee high purity and consistent quality. When sourcing this compound, researchers should look for:

  • Verified Purity: Suppliers should provide analytical data, such as HPLC chromatograms, confirming purity levels (e.g., >95%).
  • Accurate Identification: Always verify the CAS number 10391-47-6 and the correct chemical name.
  • Reputable Supply: Partnering with established chemical suppliers or direct manufacturers ensures product integrity and timely delivery.
  • Comprehensive Documentation: Access to Certificates of Analysis (CoA) and Safety Data Sheets (SDS) is essential.

We pride ourselves on being a leading supplier of biochemicals, offering high-quality Atractyligenin for your research needs. We encourage all scientists and procurement professionals to get a quote for this vital compound. Understanding the science behind our products allows us to better serve your research objectives.