Chlorhexidine Gluconate (CHG), known by its CAS number 18472-51-0, is a cornerstone in modern antisepsis and disinfection. Its efficacy stems from a well-understood mechanism of action that targets a wide spectrum of microorganisms, making it an indispensable component in numerous healthcare and personal hygiene products. Understanding the science behind CHG is key for R&D scientists and formulators looking to leverage its powerful properties.

The primary advantage of Chlorhexidine Gluconate lies in its broad-spectrum antimicrobial activity. It is highly effective against both Gram-positive and Gram-negative bacteria, yeast, and some viruses. Unlike many other antiseptics, CHG exhibits a persistent antimicrobial effect on the skin after application. This is due to its cationic nature, which causes it to bind electrostatically to negatively charged skin surfaces and microbial cell walls. This residual activity means that even after rinsing, a significant amount of CHG remains on the skin, continuing to inhibit microbial growth for several hours. This makes it an ideal choice for applications requiring prolonged protection.

The applications of Chlorhexidine Gluconate are diverse and critical. In healthcare settings, it is extensively used for skin disinfection prior to surgical procedures, reducing the risk of surgical site infections. It is also a key ingredient in healthcare personnel hand washes and surgical hand scrubs, forming a critical part of infection control protocols. Beyond the operating room, CHG solutions are utilized for general skin antisepsis, wound cleansing, and as an antiseptic oral rinse to manage gingivitis and other oral health issues. Its inclusion in over-the-counter products like hand sanitizers and antiseptic skin cleansers further highlights its widespread utility.

For product formulators and procurement managers, sourcing high-quality Chlorhexidine Gluconate is essential. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., a dedicated supplier from China, offer a 20% solution with guaranteed purity. This ensures that formulators can confidently incorporate CHG into their products, knowing they are working with a reliable pharmaceutical intermediate. When considering the purchase of Chlorhexidine Gluconate, understanding its scientific underpinnings allows for optimized formulation and application, ultimately contributing to enhanced patient safety and public health. If you are looking to buy Chlorhexidine Gluconate or require detailed specifications for CAS 18472-51-0, consulting with experienced manufacturers and suppliers is the first step.