The advancement of modern medicine is deeply intertwined with the precise synthesis of complex chemical compounds. Among these, intermediates like 5-(4-cyanophenoxy)-2,3-dihydro-1-hydroxy-2,1-benzoxaborole (CAS 906673-24-3), widely known as AN2728 or Crisaborole, play a foundational role. This boron-containing organic molecule, appearing as a white to beige powder, is a crucial component in the development of innovative therapeutics, particularly those targeting inflammatory conditions.

Scientifically, Crisaborole belongs to the class of benzoxaboroles, a group of compounds characterized by a boron atom incorporated into a benzoxazole ring system. This unique structural feature contributes to its specific biological activity and chemical reactivity. As a pharmaceutical intermediate, its primary value lies in its utility as a building block for Active Pharmaceutical Ingredients (APIs). The precise synthesis and purification of this compound are critical, as impurities can significantly impact the efficacy and safety of the final drug product.

Manufacturers who specialize in producing this intermediate, such as ourselves in China, focus on rigorous quality control measures. This includes ensuring high purity levels (often >98%) through advanced analytical techniques like HPLC and NMR. The consistent production of a well-defined chemical structure like AN2728 is essential for researchers and formulators who rely on predictable outcomes in their synthesis pathways. When you buy this compound, you are investing in a key piece of the puzzle for developing new treatments.

The application of Crisaborole in pharmaceutical research is extensive. Its role as a PDE4 inhibitor, for example, has been significant in developing treatments for inflammatory skin conditions. This therapeutic potential drives the demand for reliable suppliers who can provide the compound in various quantities, from research-scale to bulk manufacturing volumes. As a direct manufacturer, we are well-positioned to meet this demand efficiently.

For procurement managers and R&D scientists, understanding the scientific underpinnings of such intermediates is as important as knowing their price and availability. The consistency in appearance, purity, and chemical structure of 5-(4-cyanophenoxy)-2,3-dihydro-1-hydroxy-2,1-benzoxaborole is a testament to the advanced manufacturing processes employed by specialized chemical companies. We pride ourselves on delivering this scientific rigor with every batch.

In conclusion, Crisaborole (AN2728) is more than just a chemical name; it represents a critical advancement in synthetic chemistry and drug development. By partnering with experienced manufacturers and suppliers in China, you can secure a high-quality intermediate that adheres to strict scientific standards. We invite you to learn more about the science behind our products and how we can support your critical pharmaceutical projects.