Lipidomics, the comprehensive study of lipids in biological systems, is a rapidly advancing field offering profound insights into cellular function, disease mechanisms, and therapeutic targets. At the core of many lipidomics studies are high-quality, well-characterized lipids. Among these, 1,2-Dilinoleoyl-sn-Glycero-3-Phosphocholine (DLinPC) stands out due to its specific structural features and broad applicability in membrane research.

DLinPC is a phospholipid composed of a glycerol backbone esterified with two linoleic acid chains (an 18-carbon fatty acid with two cis double bonds at positions 9 and 12) and a phosphocholine headgroup. This composition gives DLinPC unique biophysical properties, including a relatively low phase transition temperature, which allows membranes incorporating it to remain fluid at physiological temperatures. This characteristic makes it an invaluable tool for researchers investigating the dynamic nature of cell membranes.

In lipidomics, DLinPC serves not only as a standard for analytical identification but also as a crucial component in creating model membranes. These models are essential for understanding protein-lipid interactions, membrane trafficking, and the role of lipids in signal transduction pathways. The consistent purity of DLinPC, supplied by reputable manufacturers, is critical for the accuracy and reproducibility of these complex experiments. When purchasing DLinPC, researchers often seek high-purity material to avoid artifacts and ensure that observed effects are solely attributable to the lipid itself.

For scientists looking to advance their lipidomics research, securing a reliable source for high-quality DLinPC is key. Manufacturers specializing in lipids play a vital role by providing meticulously characterized products. By understanding the chemical structure and biophysical behavior of DLinPC, researchers can better design experiments and interpret results, contributing to significant breakthroughs in understanding cellular biology and disease.