In the dynamic world of biotechnology, the precise manipulation and delivery of genetic material are cornerstone activities. Cationic lipids have revolutionized these processes, and DOTMA Chloride Salt (CAS 104872-42-6) is a prominent example of a molecule that has empowered significant scientific advancements. With its unique chemical structure and properties, DOTMA has become indispensable in gene transfection, liposome formulation, and various other cutting-edge applications. As a dedicated DOTMA lipid supplier in China, we are proud to contribute to this progress by providing high-purity materials.

DOTMA, characterized by its two oleyl chains and a trimethylammonium head group, functions as a potent cationic lipid. This structural arrangement imbues it with the ability to interact electrostatically with negatively charged biomolecules like DNA and RNA. When you buy DOTMA Chloride Salt, you are acquiring a compound known for its efficacy in forming stable lipid-nucleic acid complexes. These complexes are fundamental to achieving efficient cellular uptake and gene expression in research and therapeutic contexts.

Key Scientific Attributes of DOTMA Chloride Salt

The scientific community values DOTMA for several critical attributes:

  • Structure-Activity Relationship: Extensive research has elucidated the structure-activity relationship of DOTMA, highlighting how its ether linkages and the specific arrangement of its hydrophobic tails contribute to its superior performance in gene delivery compared to ester-linked analogues like DOTAP. This makes it a preferred choice for demanding applications.
  • Membrane Fusion Capabilities: The cationic nature of DOTMA facilitates the fusion of liposomes or LNPs with cellular membranes. This fusion event is crucial for releasing the therapeutic payload (e.g., mRNA, siRNA) into the cytoplasm, bypassing cellular barriers. Understanding this mechanism is key for formulators when they purchase DOTMA Chloride Salt.
  • Purity and Consistency: As a specialized biochemical, the purity and batch-to-batch consistency of DOTMA Chloride Salt are paramount. Our operations as a manufacturer ensure that we meet rigorous quality standards, typically offering a purity of 98% or higher, which is critical for reproducible experimental results.
  • Role in Lipid Nanoparticles (LNPs): DOTMA is a cornerstone lipid in many LNP formulations, working alongside helper lipids and PEGylated lipids to create stable, efficient, and stealthy delivery vehicles. The selection of a reliable DOTMA lipid supplier directly impacts the success of these complex formulations.

Sourcing DOTMA Chloride Salt from a Trusted Manufacturer

For any research or development project, securing a dependable source for critical reagents is essential. Our commitment as a DOTMA lipid supplier in China means we offer not only high-quality products but also competitive DOTMA price for research and development activities. We understand the budgetary constraints faced by many institutions and strive to provide cost-effective solutions without compromising on quality.

By choosing to buy DOTMA Chloride Salt from us, you are investing in a product backed by stringent quality control and a deep understanding of its scientific applications. Whether you are developing next-generation gene therapies or advancing fundamental research in cellular biology, our DOTMA Chloride Salt is poised to meet your needs. Contact us today to learn more about our product offerings and how we can support your innovative projects.