The scientific community is increasingly recognizing the potential of targeted molecular interventions to address complex biological processes. ISRIB (trans-isomer), a compound that precisely inhibits the Integrated Stress Response (ISR), stands out for its intriguing mechanism of action and broad therapeutic implications. As a dedicated manufacturer and supplier of advanced research chemicals, we provide high-purity ISRIB to fuel cutting-edge scientific inquiry.

At its core, ISRIB (CAS 1597403-47-8) operates by selectively targeting the eIF2α/eIF2S1 Ser51 phosphorylation pathway. This pathway is a central regulator of protein synthesis under cellular stress. By inhibiting this critical step, ISRIB effectively reverses the downstream consequences of ISR activation, which can include impaired protein synthesis and the formation of stress granules. Understanding this mechanism is vital for researchers who buy ISRIB for their studies.

The scientific literature details ISRIB's significant impact on cellular and organismal function. Studies have shown that ISRIB can restore cognitive function in aged mice and even reverse memory deficits resulting from brain injuries. This has positioned ISRIB as a promising candidate for research into neurodegenerative diseases and cognitive disorders. For researchers aiming to make breakthroughs in these areas, securing a reliable source for ISRIB is essential.

We are committed to supporting scientific advancement by offering ISRIB with a purity exceeding 99%. As a leading chemical supplier in China, we ensure that our product's quality is consistently high, enabling reproducible experimental outcomes. Our competitive price structure makes this potent research tool accessible to a wider range of laboratories. Whether you are a pharmaceutical company, a research institution, or an academic laboratory, we are your trusted partner for procuring this vital compound.

When you decide to purchase ISRIB, consider the advantages of sourcing from an established manufacturer. We provide detailed specifications, safety data, and responsive support to ensure your research proceeds smoothly. Explore the groundbreaking potential of ISRIB in your next research project and experience the difference that quality and reliability make. Inquire today about our ISRIB offerings and how we can support your scientific goals.