The Science Behind Synthesis: Exploring the Properties of 4-Amino-2-chloro-6,7-dimethoxyquinazoline
The efficacy of a synthesized pharmaceutical compound is intrinsically linked to the purity and precise characteristics of the chemical intermediates used in its production. 4-Amino-2-chloro-6,7-dimethoxyquinazoline (CAS 23680-84-4) is a prime example of such an intermediate, critical for the synthesis of significant pharmaceutical agents like Terazosin and Doxazosin. Understanding its properties is key for chemists and manufacturers.
NINGBO INNO PHARMCHEM CO.,LTD. provides comprehensive data on the physical and chemical properties of 4-Amino-2-chloro-6,7-dimethoxyquinazoline. This white to off-white crystalline solid possesses a high melting point, typically in the range of 262-268 °C (with decomposition), indicating its stability under standard processing conditions. Its molecular formula is C10H10ClN3O2, with a molecular weight of 239.66 g/mol. The compound exhibits limited solubility in water but is generally soluble in DMSO and slightly soluble in heated methanol, which are common solvents in organic synthesis.
The stringent specifications of 4-Amino-2-chloro-6,7-dimethoxyquinazoline, including a purity assay of ≥99.5% (via HPLC), a loss on drying of ≤0.5%, and residue on ignition of ≤0.1%, underscore its suitability for demanding applications. These details are crucial for ensuring the success of complex chemical synthesis pathways, particularly those involved in the manufacturing of cardiovascular drugs. For clients undertaking Terazosin hydrochloride synthesis or requiring a reliable Doxazosin intermediate, NINGBO INNO PHARMCHEM CO.,LTD. ensures that each batch meets the highest standards for pharmaceutical intermediates.
By providing detailed insights into the science behind our products, such as the properties of 4-Amino-2-chloro-6,7-dimethoxyquinazoline (CAS 23680-84-4), NINGBO INNO PHARMCHEM CO.,LTD. empowers chemists and researchers to achieve optimal results in their synthesis and development efforts.
Perspectives & Insights
Logic Thinker AI
“provides comprehensive data on the physical and chemical properties of 4-Amino-2-chloro-6,7-dimethoxyquinazoline.”
Molecule Spark 2025
“This white to off-white crystalline solid possesses a high melting point, typically in the range of 262-268 °C (with decomposition), indicating its stability under standard processing conditions.”
Alpha Pioneer 01
“The compound exhibits limited solubility in water but is generally soluble in DMSO and slightly soluble in heated methanol, which are common solvents in organic synthesis.”