The Science of (D-ALA1)-Peptide T: A Synthetic Octapeptide for Research
The field of medicinal chemistry is continually exploring novel compounds to address pressing health issues. Synthetic peptides, with their precise structures and targeted biological activities, are at the forefront of this exploration. One such compound that has significant scientific merit is (D-ALA1)-Peptide T (CAS 106362-33-8), a synthetic octapeptide that holds promise in antiviral research, particularly in relation to HIV and AIDS.
Understanding the Molecular Architecture and Function
(D-ALA1)-Peptide T is an octapeptide, meaning it consists of eight amino acid residues linked by peptide bonds. Its chemical formula is C35H55N9O16, with a molecular weight of approximately 857.86 g/mol. The defining feature of this peptide is the presence of D-alanine at the first amino acid position. This chiral modification from the more common L-alanine is crucial; it confers resistance to enzymatic cleavage, thereby enhancing the peptide's stability and prolonging its biological half-life. This improved pharmacokinetic profile is a significant advantage for any compound considered for therapeutic development.
The scientific interest in (D-ALA1)-Peptide T is largely driven by its structural similarity to a segment of the HIV-1 envelope glycoprotein gp120. HIV utilizes gp120 to attach to CD4 receptors on host cells, a critical step for viral entry and infection. (D-ALA1)-Peptide T is hypothesized to act as a viral entry inhibitor by competitively binding to these cellular receptors or to the viral gp120 protein. By blocking this essential interaction, the peptide can impede the virus's ability to infect cells, offering a potential strategy for therapeutic intervention against HIV.
Reliable Sourcing for Scientific Advancement
For researchers and institutions involved in antiviral studies, securing a reliable supply of high-purity (D-ALA1)-Peptide T is paramount. NINGBO INNO PHARMCHEM CO.,LTD. is a reputable manufacturer and supplier of specialized peptides and pharmaceutical intermediates. We provide (D-ALA1)-Peptide T with guaranteed purity levels, typically above 98.0%, ensuring that your research is based on compounds of the highest quality. As a dedicated manufacturer in China, we are committed to offering competitive pricing and ensuring efficient delivery to support scientific progress worldwide. When you need to buy this crucial synthetic octapeptide, choose a partner that prioritizes quality and consistency.
The scientific utility of (D-ALA1)-Peptide T extends to various research applications, including biochemical assays, studies on cellular receptor binding, and the development of drug candidates targeting viral entry mechanisms. Its well-characterized properties make it an invaluable tool for advancing our understanding of viral pathogenesis and treatment strategies.
In summary, (D-ALA1)-Peptide T is a scientifically significant synthetic peptide with compelling antiviral properties. Its unique chemical structure and mechanism of action make it a valuable asset in HIV and AIDS research. Ensuring access to high-quality material from reliable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. is fundamental to achieving breakthroughs in this critical area of medical science.
Perspectives & Insights
Agile Reader One
“The defining feature of this peptide is the presence of D-alanine at the first amino acid position.”
Logic Vision Labs
“This chiral modification from the more common L-alanine is crucial; it confers resistance to enzymatic cleavage, thereby enhancing the peptide's stability and prolonging its biological half-life.”
Molecule Origin 88
“This improved pharmacokinetic profile is a significant advantage for any compound considered for therapeutic development.”