Understanding the scientific underpinnings of critical reagents is essential for successful research and development. DOTAP Chloride (CAS 132172-61-3), a key cationic lipid in the biotechnology and pharmaceutical sectors, is no exception. This article aims to provide a detailed look at its scientific properties, the importance of purity, and how to approach procurement from a trusted DOTAP chloride manufacturer.

DOTAP Chloride, chemically known as 1,2-Dioleoyl-3-trimethylammonium-propane chloride, is characterized by its amphipathic nature. It possesses a hydrophilic headgroup containing a quaternary ammonium cation and two lipophilic oleoyl chains. This structure allows it to self-assemble into lipid bilayers and form stable complexes with nucleic acids. Its molecular formula, C42H80ClNO4, and a molecular weight of approximately 698.56 g/mol, define its precise chemical identity.

A critical aspect for any user of DOTAP Chloride is its purity. The sources we have reviewed indicate that high purity is typically above 98%, with many suppliers specifying 99% or higher, often verified by HPLC. Other important specifications include moisture content (often <2.0%), heavy metal content (<0.001%), and minimal residual solvents. These parameters are vital because impurities can affect transfection efficiency, lead to unexpected cellular responses, or compromise the stability of lipid nanoparticles. For applications like mRNA vaccine production, where reproducibility and safety are paramount, sourcing from a supplier that guarantees lot-to-lot consistency and provides comprehensive Certificates of Analysis (CoA) is crucial.

The physical form of DOTAP Chloride is usually described as a white to off-white solid or powder. Its hygroscopic nature means it readily absorbs moisture from the air, necessitating storage under inert gas at low temperatures (typically -20°C) to maintain its integrity and prevent degradation. Understanding these handling requirements is key for laboratory personnel. When considering where to buy DOTAP chloride, it's beneficial to choose a supplier that provides clear storage and handling guidelines.

Procurement of DOTAP Chloride often involves seeking out reliable manufacturers and suppliers. NINGBO INNO PHARMCHEM CO.,LTD. is a recognized DOTAP chloride supplier in China known for its commitment to quality. Our production processes emphasize high purity and consistent quality control, ensuring that our clients receive a reliable product for their demanding applications. Whether you are involved in basic research, gene therapy development, or large-scale LNP formulation, our high-grade DOTAP Chloride is manufactured to meet your needs.

We understand the importance of timely and cost-effective sourcing. Therefore, we offer competitive DOTAP chloride price options, especially for bulk purchases. By prioritizing quality, consistency, and customer service, we aim to be your preferred partner for all your DOTAP Chloride requirements. Engaging with us means gaining access to a scientifically sound product backed by rigorous quality assurance, enabling you to push the boundaries of innovation in your respective fields.