In the realm of pharmaceutical research and development, understanding the precise molecular mechanisms and applications of specific compounds is crucial for scientific progress. Nintedanib, identified by its CAS number 656247-17-5, is a prime example of such a compound, recognized globally for its potent activity as an inhibitor of multiple receptor tyrosine kinases. Specifically, Nintedanib targets VEGFR, PDGFR, and FGFR, making it a subject of intense study in areas like oncology and the treatment of fibrotic diseases.

As a leading manufacturer and supplier in the fine chemical industry, we are dedicated to providing researchers with access to high-purity Nintedanib free base. Our commitment stems from understanding its critical role in advancing therapeutic discoveries. When you choose to buy Nintedanib free base from a reputable manufacturer, you are ensuring the integrity and reliability of your experimental outcomes. We offer competitive pricing for this essential research chemical.

The scientific significance of Nintedanib lies in its ability to disrupt several key signaling pathways that are dysregulated in various pathologies. In cancer research, its inhibition of VEGFR impedes tumor angiogenesis, thereby starving tumors of blood supply and inhibiting their growth and metastasis. Concurrently, its effects on PDGFR and FGFR are vital for understanding and combating fibrotic diseases, such as idiopathic pulmonary fibrosis, where excessive tissue remodeling occurs. This dual action highlights its broad therapeutic potential and its importance in scientific inquiry.

For procurement, Nintedanib free base is typically available as a yellow solid powder. Its chemical formula is C31H33N5O4, and its molecular weight is approximately 539.62. The purity of the compound is a non-negotiable aspect for reliable scientific results. As a dedicated manufacturer, we ensure that our Nintedanib free base meets rigorous quality standards, typically exceeding 98% purity, and we provide comprehensive documentation to support its use.

Researchers seeking to integrate Nintedanib free base into their projects can rely on our efficient supply chain and responsive customer service. We understand the time-sensitive nature of research and strive to provide timely delivery. Our goal is to be more than just a supplier; we aim to be a trusted partner in your scientific journey. Obtaining a quote from us for your Nintedanib free base requirements will demonstrate our commitment to both quality and value.

In conclusion, Nintedanib free base (CAS 656247-17-5) is a scientifically significant compound with profound implications for cancer and fibrosis research. As a reliable manufacturer and supplier, we are equipped to meet your demands for this critical pharmaceutical intermediate. We encourage you to contact us to learn more about our product and to request a quote, thereby securing a high-quality compound for your important research endeavors.