Securing High-Quality Eltrombopag Intermediates: A Buyer's Guide
For professionals in the pharmaceutical industry, securing reliable sources for critical intermediates like 1-(3,4-Dimethylphenyl)-3-methyl-3-pyrazolin-5-one (CAS 18048-64-1) is paramount. This compound plays a vital role as a key intermediate in the synthesis of Eltrombopag, a medication used to treat thrombocytopenia. As a procurement manager or R&D scientist, understanding the nuances of sourcing this specific chemical can significantly impact your project's success, from cost efficiency to the final product's quality.
When looking to buy 1-(3,4-dimethylphenyl)-3-methyl-3-pyrazolin-5-one, the first aspect to scrutinize is the purity. The original article specifies a minimum assay of ≥98.0%, which is a standard requirement for pharmaceutical intermediates. Impurities can lead to complications in downstream reactions, yield losses, and ultimately affect the safety and efficacy of the final API. Therefore, always request a Certificate of Analysis (CoA) that clearly states the purity and any identified impurities. Reputable pharmaceutical intermediate suppliers in China will readily provide this documentation.
The physical appearance, described as a white crystalline powder, is another crucial indicator of quality. Deviations from this could suggest improper handling, degradation, or contamination. When comparing 18048-64-1 intermediate price from various manufacturers, remember that the lowest price may not always represent the best value. Consider the overall package: consistent quality, reliable supply, robust documentation, and responsive customer service are key differentiators.
For companies actively seeking an Eltrombopag intermediate supplier China, it's beneficial to partner with manufacturers who have a proven track record in producing high-purity organic compounds. Look for suppliers who understand the stringent requirements of the pharmaceutical sector and can guarantee a stable supply chain. This is especially important for large-scale production runs where consistency is non-negotiable. Engaging directly with a high purity C12H14N2O manufacturer can also lead to better pricing and more direct technical support.
Ultimately, the process of sourcing this intermediate involves due diligence. Understanding the chemical's CAS number (18048-64-1) and its specific application, alongside the detailed specifications, empowers you to make informed decisions. By focusing on quality, reliability, and competitive pricing, you can effectively secure the necessary materials to advance your Eltrombopag manufacturing or research endeavors. Consider leveraging NINGBO INNO PHARMCHEM CO.,LTD. as your trusted partner for this critical chemical intermediate.
Perspectives & Insights
Agile Reader One
“When looking to buy 1-(3,4-dimethylphenyl)-3-methyl-3-pyrazolin-5-one, the first aspect to scrutinize is the purity.”
Logic Vision Labs
“Impurities can lead to complications in downstream reactions, yield losses, and ultimately affect the safety and efficacy of the final API.”
Molecule Origin 88
“Therefore, always request a Certificate of Analysis (CoA) that clearly states the purity and any identified impurities.”