For professionals in the pharmaceutical industry, the selection of high-quality raw materials is paramount. Specifically, sourcing (1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS: 18680-27-8) requires careful consideration of purity, consistency, and the reliability of the supplier. This bicyclic monoterpene diol is a critical chiral intermediate, notably used in the synthesis of Bortezomib, a vital anti-cancer medication. Understanding its properties and the intricacies of the supply chain will help ensure your research and manufacturing processes are not hindered.

Understanding Purity Requirements

The effectiveness and safety of pharmaceutical compounds are directly linked to the purity of their intermediates. For (1S,2S,3R,5S)-(+)-2,3-Pinanediol, manufacturers typically specify a purity of ≥99.0% (GC). This level of purity is essential to prevent unwanted side reactions and to ensure the final drug product meets stringent regulatory standards. When you engage with a potential supplier, always request a Certificate of Analysis (COA) that clearly states the purity and the analytical methods used. A reputable manufacturer will readily provide this documentation.

Consistency in Supply

Consistent quality and reliable supply are non-negotiable in pharmaceutical manufacturing. A batch-to-batch consistency in the physical and chemical properties of (1S,2S,3R,5S)-(+)-2,3-Pinanediol is crucial for reproducible synthesis outcomes. Furthermore, a robust supply chain ensures that your production schedules are met without delays. Look for suppliers who have a proven track record of on-time delivery and who can demonstrate their manufacturing capacity and quality control processes. Considering suppliers based in China can offer competitive pricing and a broad manufacturing base, but thorough due diligence is always recommended.

Key Considerations When Buying

When looking to buy (1S,2S,3R,5S)-(+)-2,3-Pinanediol, key questions to ask potential manufacturers and suppliers include:

  • What is your typical lead time for orders of varying quantities?
  • Can you provide detailed specifications and SDS for the product?
  • What are your quality assurance and quality control (QA/QC) procedures?
  • Do you offer custom synthesis or specific packaging options?
  • What is the typical price range for this intermediate?

Engaging with established chemical companies that specialize in pharmaceutical intermediates will provide the assurance you need. They understand the rigorous demands of the industry and are equipped to meet them. Prioritizing a supplier that values transparency, quality, and customer service will build a strong foundation for your project success.

In summary, selecting the right manufacturer for (1S,2S,3R,5S)-(+)-2,3-Pinanediol is a strategic decision. By focusing on purity, consistency, and the supplier's commitment to quality, pharmaceutical professionals can secure a vital component for their life-saving drug syntheses. We, as a dedicated chemical supplier, are committed to meeting these exacting standards for our clients worldwide.