The Significance of 3-Fluoro-4'-pentyl-biphenylboronic Acid in Pharmaceutical R&D
The pharmaceutical industry is in a perpetual state of innovation, driven by the need to discover and develop new treatments for a myriad of diseases. Central to this endeavor is the field of organic synthesis, where specific chemical intermediates act as linchpins in the creation of complex molecular structures. NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of providing these essential building blocks, including the highly versatile 3-Fluoro-4'-pentyl-biphenylboronic acid (CAS: 163129-96-0).
This particular boronic acid derivative plays a critical role in pharmaceutical research and development due to its utility in constructing biaryl systems. Biaryl motifs are common in many biologically active molecules, including a significant number of approved drugs. The Suzuki-Miyaura coupling reaction, a palladium-catalyzed cross-coupling process, is the primary method through which these structures are efficiently synthesized, and 3-Fluoro-4'-pentyl-biphenylboronic acid is an excellent substrate for this reaction. Its molecular formula, C17H20BFO2, and its characteristic white powder appearance, coupled with a high assay of ≥98.0%, underscore its suitability for demanding synthetic applications.
The incorporation of a fluorine atom into organic molecules is a strategy frequently employed in medicinal chemistry to modulate a compound's pharmacokinetic properties. Fluorine can enhance lipophilicity, leading to improved cell membrane penetration, and increase metabolic stability, prolonging a drug's half-life in the body. The pentyl group on the biphenyl structure further adds to the molecule's versatility, influencing its steric and electronic properties, which can be finely tuned during the drug design process. These attributes make 3-Fluoro-4'-pentyl-biphenylboronic acid a valuable tool for medicinal chemists seeking to optimize drug candidates.
NINGBO INNO PHARMCHEM CO.,LTD. is proud to contribute to the advancement of pharmaceutical R&D by supplying intermediates like 3-Fluoro-4'-pentyl-biphenylboronic acid. Our commitment to quality, consistency, and efficient supply chain management ensures that our clients can rely on us for their critical chemical needs. By providing access to such specialized compounds, we empower researchers to accelerate their discovery pipelines and bring innovative medicines to market more effectively.
The strategic importance of intermediates like 3-Fluoro-4'-pentyl-biphenylboronic acid cannot be overstated. They are the fundamental components that enable the complex synthesis required for modern drug development. NINGBO INNO PHARMCHEM CO.,LTD. remains dedicated to being a leading provider of these crucial materials, fostering innovation in the pharmaceutical sector.
Perspectives & Insights
Silicon Analyst 88
“These attributes make 3-Fluoro-4'-pentyl-biphenylboronic acid a valuable tool for medicinal chemists seeking to optimize drug candidates.”
Quantum Seeker Pro
“is proud to contribute to the advancement of pharmaceutical R&D by supplying intermediates like 3-Fluoro-4'-pentyl-biphenylboronic acid.”
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“Our commitment to quality, consistency, and efficient supply chain management ensures that our clients can rely on us for their critical chemical needs.”