The Significance of N-Carbobenzyloxyglycine (CAS 1138-80-3) in Pharmaceutical Intermediate Synthesis
The pharmaceutical industry relies heavily on a diverse array of chemical compounds as building blocks for synthesizing life-saving drugs. Among these, N-Carbobenzyloxyglycine (CAS 1138-80-3) holds a significant position as a key pharmaceutical intermediate. This protected amino acid, often referred to as Z-Gly-OH, is valued for its specific chemical characteristics and its utility in the synthesis of complex organic molecules with therapeutic potential.
N-Carbobenzyloxyglycine, appearing as a white crystalline powder, is characterized by its chemical formula C10H11NO4 and a molecular weight of 209.2. Its structure features the glycine amino acid backbone protected by a benzyloxycarbonyl (Cbz) group. This protection is essential in multi-step synthetic processes, preventing undesired reactions at the amino group while allowing the carboxyl group to participate in necessary transformations. Its reliable melting point range (118-122°C) and solubility properties make it a predictable and manageable reagent for pharmaceutical manufacturers.
As a crucial chemical intermediate, N-Carbobenzyloxyglycine is instrumental in the development of novel pharmaceutical agents. Its application extends to the synthesis of peptides with therapeutic activity, as well as other complex organic compounds that form the active pharmaceutical ingredients (APIs) of various medications. When considering to buy N-Carbobenzyloxyglycine online, it is vital to partner with suppliers who can guarantee pharmaceutical-grade purity and consistency. Many reputable manufacturers in China are at the forefront of supplying this critical compound, ensuring adherence to stringent quality controls.
The widespread use of this CAS 1138-80-3 chemical intermediate underscores its importance in the drug discovery pipeline. Researchers and developers depend on its predictable reactivity and high purity to streamline their synthesis processes and accelerate the journey from lab to clinic. By leveraging the capabilities of N-Carbobenzyloxyglycine, the pharmaceutical sector continues to innovate and bring essential treatments to patients worldwide.
Perspectives & Insights
Logic Thinker AI
“Its reliable melting point range (118-122°C) and solubility properties make it a predictable and manageable reagent for pharmaceutical manufacturers.”
Molecule Spark 2025
“As a crucial chemical intermediate, N-Carbobenzyloxyglycine is instrumental in the development of novel pharmaceutical agents.”
Alpha Pioneer 01
“Its application extends to the synthesis of peptides with therapeutic activity, as well as other complex organic compounds that form the active pharmaceutical ingredients (APIs) of various medications.”