The Significance of Purity: Sourcing 4-Phenyl-2-pyrrolidinone for Research
In the realm of chemical synthesis, particularly for pharmaceutical research and development, the purity of starting materials and intermediates is a non-negotiable factor. 4-Phenyl-2-pyrrolidinone (CAS 1198-97-6) is a prime example of an intermediate where consistent, high purity directly impacts the success of downstream applications. This compound is sought after for its potential role in synthesizing biologically active molecules, including those with nootropic and anticonvulsant properties, making its quality a critical consideration for any research scientist or procurement manager.
The chemical profile of 4-Phenyl-2-pyrrolidinone includes its molecular formula C10H11NO and a molecular weight of 161.20 g/mol. Typically supplied as a white to light yellow crystalline powder, its defined melting point range (72.0-78.0°C) is a key indicator of its purity. For research purposes, achieving predictable and reproducible results is paramount. Impurities, even in small amounts, can lead to unexpected side reactions, altered product yields, or compromised biological activity in the final synthesized compounds. Therefore, sourcing material with guaranteed purity, often cited as 97% or 98%+, is a fundamental requirement.
When embarking on the process to buy 4-Phenyl-2-pyrrolidinone, prospective buyers should meticulously vet their potential suppliers. This involves looking beyond just the price point to focus on the supplier's commitment to quality assurance. A reputable manufacturer will provide readily accessible Certificates of Analysis (CoA) for each batch, detailing analytical results for purity, identity, and impurity profiles. Furthermore, suppliers who offer free samples for initial evaluation allow researchers to perform their own quality checks and ensure compatibility with their specific synthetic protocols.
For companies engaged in advanced organic synthesis or pharmaceutical R&D, establishing a relationship with a dependable chemical supplier is key. This often means looking for manufacturers with robust quality control systems, transparent documentation practices, and a proven track record in delivering pharmaceutical intermediates. The ability to secure a stable supply of high-purity 4-Phenyl-2-pyrrolidinone not only supports ongoing research but also facilitates scalability towards larger production runs if the synthesized compounds prove successful. Prioritizing purity from the outset saves time, resources, and ultimately contributes to the integrity of the final pharmaceutical product.
Perspectives & Insights
Bio Analyst 88
“This involves looking beyond just the price point to focus on the supplier's commitment to quality assurance.”
Nano Seeker Pro
“A reputable manufacturer will provide readily accessible Certificates of Analysis (CoA) for each batch, detailing analytical results for purity, identity, and impurity profiles.”
Data Reader 7
“Furthermore, suppliers who offer free samples for initial evaluation allow researchers to perform their own quality checks and ensure compatibility with their specific synthetic protocols.”