In the intricate world of pharmaceutical synthesis, certain chemical intermediates play a pivotal role, acting as the backbone for life-saving medications. One such compound is 1-Benzyl-4-piperidinecarboxaldehyde, identified by its CAS number 22065-85-6. For procurement managers and R&D scientists in the pharmaceutical industry, understanding its significance and sourcing it reliably is paramount.

Why is 1-Benzyl-4-piperidinecarboxaldehyde Crucial?

This compound is widely recognized as a key intermediate in the synthesis of Donepezil hydrochloride. Donepezil is a cornerstone medication used globally for the symptomatic treatment of Alzheimer's disease, aiming to improve cognitive function by inhibiting acetylcholinesterase. The structural integrity and purity of intermediates like 1-Benzyl-4-piperidinecarboxaldehyde directly influence the efficacy and safety of the final Active Pharmaceutical Ingredient (API). Therefore, sourcing this chemical with a high purity assay, typically 98.0% or above as determined by GC, is non-negotiable for pharmaceutical manufacturers.

Understanding its Chemical Properties

1-Benzyl-4-piperidinecarboxaldehyde, with the molecular formula C13H17NO and a molecular weight of approximately 203.28 g/mol, presents as a colorless oil. Its chemical structure, featuring an aldehyde group on a piperidine ring substituted with a benzyl group, makes it a versatile building block for various organic transformations. These properties are critical for its role in complex, multi-step synthetic routes characteristic of pharmaceutical production. Understanding these attributes helps procurement specialists identify suitable suppliers who can consistently deliver material meeting stringent specifications.

The Advantage of Sourcing from China Manufacturers

China has emerged as a global powerhouse in the manufacturing of fine chemicals and pharmaceutical intermediates. For companies looking to buy 1-Benzyl-4-piperidinecarboxaldehyde, partnering with reputable Chinese manufacturers offers distinct advantages. These suppliers often possess advanced manufacturing capabilities, stringent quality control systems, and the ability to produce at scale, from kilograms to metric tons. This ensures a stable and cost-effective supply chain, which is vital for uninterrupted drug production. When considering a supplier, it is essential to look for those who can provide detailed technical data sheets, Certificates of Analysis (CoA), and demonstrate compliance with international quality standards.

Key Considerations for Procurement Managers

When tasked with sourcing CAS 22065-85-6, procurement managers should focus on:

  • Supplier Reliability: Choose manufacturers with a proven track record in supplying pharmaceutical intermediates.
  • Purity and Specifications: Ensure the product meets the required purity levels (e.g., ≥98.0% GC) and other critical parameters.
  • Production Capacity: Verify the supplier's ability to meet your volume requirements, from R&D quantities to commercial batches.
  • Regulatory Compliance: Confirm that the manufacturing processes align with relevant pharmaceutical industry regulations.
  • Pricing and Lead Times: Obtain competitive quotes and understand the lead times for delivery to manage your production schedules effectively.

NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier and manufacturer specializing in high-quality pharmaceutical intermediates like 1-Benzyl-4-piperidinecarboxaldehyde. We understand the critical nature of these compounds and are committed to providing reliable supply chains and exceptional product quality to support your pharmaceutical development and manufacturing goals. Reach out to us for your procurement needs.