For procurement managers and R&D scientists in the pharmaceutical and fine chemical industries, securing a reliable supply of critical intermediates is paramount. 1-Boc-3-iodoazetidine (CAS 254454-54-1) stands out as a versatile building block, particularly valued in organic synthesis for its unique azetidine ring structure and the reactive iodine atom. Understanding how to effectively source this compound can significantly impact project timelines and cost-efficiency. This guide aims to provide procurement professionals with actionable insights into buying 1-Boc-3-iodoazetidine.

Understanding 1-Boc-3-iodoazetidine

1-Boc-3-iodoazetidine, a white powder with a molecular weight of 283.11 g/mol, is characterized by the presence of a tert-butyloxycarbonyl (Boc) protecting group on the azetidine nitrogen and an iodine atom at the 3-position. This structural arrangement makes it an excellent precursor for various chemical transformations, including nucleophilic substitution reactions. Its primary application lies in the synthesis of complex molecules, notably in the development of novel pharmaceuticals and agrochemicals. As a specialized pharmaceutical intermediate, its purity and consistent quality are non-negotiable.

Key Considerations for Purchasing: Purity, Specifications, and Supplier Reliability

When evaluating suppliers for 1-Boc-3-iodoazetidine, procurement managers should prioritize several key factors:

  • Purity Levels: Look for products with a minimum purity of 98%. High purity is essential to avoid side reactions and ensure the integrity of the final synthesized product. Always request a Certificate of Analysis (CoA) to verify specifications.
  • Supplier Reputation and Origin: Many reliable manufacturers and suppliers are located in China, offering competitive pricing and substantial supply capacities. However, vetting these suppliers for quality control processes, certifications (like ISO), and a track record of consistent delivery is crucial.
  • Packaging and Delivery: Ensure the supplier offers appropriate packaging to maintain product integrity during transit and can meet your required delivery schedules. Understanding Incoterms like FOB or CIF will also be beneficial when negotiating purchase terms.
  • Pricing and Minimum Order Quantities (MOQs): Obtain quotes from multiple suppliers to compare pricing. Be aware of MOQs and inquire about sample availability for quality testing before committing to a large order.

Navigating the Procurement Process: From Inquiry to Order

The process of buying 1-Boc-3-iodoazetidine typically begins with an inquiry to potential manufacturers or distributors. Clearly state your requirements, including the CAS number (254454-54-1), desired quantity, purity specifications, and delivery location. Reputable suppliers will respond promptly with detailed quotations and product information. It is advisable to establish a strong relationship with a select few suppliers to ensure a stable supply chain, especially for ongoing research projects or commercial production. Remember, sourcing high-quality pharmaceutical intermediates like 1-Boc-3-iodoazetidine from a trusted manufacturer is an investment in the success of your R&D and production efforts.

For procurement managers seeking a dependable supplier of 1-Boc-3-iodoazetidine in China, exploring options from established chemical manufacturers is a strategic move. Many provide excellent technical support and are accustomed to international trade, making the purchase process smoother. By focusing on these critical aspects, you can secure the quality and quantity of this vital intermediate needed for your synthesis needs.