For procurement managers and R&D scientists in the pharmaceutical sector, sourcing high-quality chemical intermediates is paramount to successful drug development. One such crucial compound is 1-Bromo-3,5-Dimethoxybenzene (CAS 20469-65-2). This article serves as a guide for buyers looking to purchase this vital building block, focusing on its specifications, applications, and the importance of choosing a reputable manufacturer and supplier.

1-Bromo-3,5-Dimethoxybenzene is primarily recognized for its role as a key intermediate in the synthetic preparation of pharmaceutical inhibitors. Its molecular structure, C8H9BrO2, makes it particularly useful in advanced cross-coupling reactions, a staple in modern organic synthesis for creating complex molecular architectures. The purity of this compound is critical; specifications often require an assay of ≥ 98.0%. When you buy 1-Bromo-3,5-Dimethoxybenzene, ensure that the supplier provides detailed Certificates of Analysis (CoA) confirming this purity level, along with other essential quality parameters like moisture and impurity levels.

The primary application of 1-Bromo-3,5-Dimethoxybenzene lies in its utility as a starting material or intermediate for synthesizing active pharmaceutical ingredients (APIs). Researchers leverage its reactivity in various coupling reactions, such as Suzuki, Sonogashira, or Buchwald-Hartwig couplings, to build sophisticated drug candidates. Understanding these applications allows procurement managers to better assess the requirements for their R&D pipelines.

When it comes to purchasing, identifying a reliable manufacturer and supplier is key. Factors to consider include the supplier's manufacturing capabilities, quality control systems (e.g., ISO certifications), and their ability to provide consistent supply and competitive pricing. For businesses seeking to buy this compound, looking for suppliers in regions known for chemical manufacturing expertise, such as China, can offer cost-effective solutions without compromising on quality. Inquiries about price and bulk purchase options should always be directed to the sales department of potential suppliers.

In summary, for effective pharmaceutical synthesis, securing a dependable source of 1-Bromo-3,5-Dimethoxybenzene (CAS 20469-65-2) with high purity is essential. By focusing on stringent specifications and partnering with reputable chemical manufacturers and suppliers, procurement professionals can ensure the smooth progression of their research and development projects.