For procurement managers and R&D scientists in the chemical and pharmaceutical industries, sourcing high-quality intermediates like 1-Bromo-3-chloropropane (CAS: 109-70-6) is paramount. Understanding its specifications, applications, and how to engage with manufacturers and suppliers is crucial for a successful purchasing process. This article aims to demystify the procurement of this essential organic synthesis intermediate.

1-Bromo-3-chloropropane, a haloalkane, is characterized by its chemical formula C3H6BrCl. It typically appears as a colorless, transparent liquid. Its physical properties, such as a boiling point of 144-145°C and a density of 1.592 g/mL, are critical for handling and reaction design. The high purity, often exceeding 99.5%, with minimal moisture content (≤0.05%), makes it ideal for demanding chemical reactions where impurities can compromise the final product.

The primary value of 1-Bromo-3-chloropropane lies in its role as a versatile intermediate in organic synthesis. It serves as a key building block in the pharmaceutical industry for the creation of various active pharmaceutical ingredients (APIs). For instance, its structure is leveraged in synthesizing anti-inflammatory drugs and other complex organic molecules. Beyond pharmaceuticals, it is also used in the agrochemical sector and in the broader production of specialty chemicals. Researchers often look to buy this compound for its ability to introduce specific functional groups into larger molecules.

When considering where to purchase 1-Bromo-3-chloropropane, identifying reliable manufacturers and suppliers is key. Companies looking for this intermediate should prioritize those that provide detailed Certificates of Analysis (COA) and Safety Data Sheets (SDS). The CAS number 109-70-6 is a universal identifier that should be used in all inquiries. Engaging with a Chinese manufacturer can often provide a competitive advantage in terms of both price and volume. A good supplier will not only offer competitive pricing but also guarantee consistent quality and a stable supply chain, which are critical for uninterrupted production cycles.

For procurement professionals aiming to secure a consistent supply of 1-Bromo-3-chloropropane, it is advisable to establish direct relationships with reputable chemical manufacturers. This approach allows for better negotiation on pricing and ensures that the product specifications meet exact requirements. Many companies specialize in providing bulk quantities and custom packaging to suit diverse industrial needs. Therefore, before making a purchase, thoroughly vet potential suppliers, checking for their manufacturing capabilities, quality control processes, and customer service responsiveness. Understanding the market dynamics and engaging with experienced suppliers will ensure you acquire this vital organic synthesis intermediate efficiently and cost-effectively.