For professionals in the pharmaceutical industry, securing a consistent and high-quality supply of chemical intermediates is paramount. 1-Bromo-4-chlorobutane (CAS 6940-78-9) stands out as a vital organic intermediate, frequently sought after for its utility in the synthesis of various Active Pharmaceutical Ingredients (APIs). This article aims to guide pharmaceutical procurement managers and R&D scientists in identifying reliable manufacturers and suppliers for this critical compound, ensuring smooth production processes and product integrity.

Understanding the Significance of 1-Bromo-4-Chlorobutane in Pharma

1-Bromo-4-chlorobutane is a bifunctional alkyl halide, meaning it possesses both a bromine and a chlorine atom attached to a four-carbon chain. This specific structure makes it a versatile building block in organic chemistry, particularly in nucleophilic substitution reactions. In pharmaceutical synthesis, it's employed to introduce specific structural motifs or to elongate carbon chains within complex molecules. Its purity is a critical factor; impurities can lead to side reactions, reduced yields, and ultimately, compromised drug quality. Therefore, when looking to buy 1-Bromo-4-chlorobutane, prioritizing suppliers who guarantee high purity (often 99% or higher) is essential.

Key Considerations When Sourcing from Manufacturers and Suppliers

  • Purity and Quality Assurance: Always request a Certificate of Analysis (COA) for any batch. This document should detail the purity, assay, and any impurities present. A reputable manufacturer will have robust quality control measures in place.
  • Production Capacity and Reliability: For pharmaceutical production, consistent supply is non-negotiable. Investigate the supplier's production capacity (e.g., tons per month) and their track record for on-time delivery. A supplier with years of export experience often signifies better logistical handling and understanding of international trade.
  • Pricing and MOQ: While quality is paramount, cost-effectiveness is also a key driver for procurement. Compare prices from different manufacturers but always balance this against quality and reliability. Understand their Minimum Order Quantity (MOQ) to ensure it aligns with your project needs, whether for R&D or large-scale manufacturing.
  • Regulatory Compliance: Ensure the supplier adheres to relevant industry standards and can provide necessary documentation, such as MSDS (Material Safety Data Sheet), which is crucial for safe handling and compliance.

Finding the Right Manufacturer in China

China has emerged as a significant global hub for fine chemical and pharmaceutical intermediate manufacturing. Many companies offer 1-Bromo-4-chlorobutane, but diligence is required. Look for suppliers who clearly state their capabilities, such as having a dedicated R&D team, state-of-the-art facilities, and a commitment to environmental responsibility. Companies emphasizing technological innovation and customer-centric service are generally more reliable partners.

When you need to purchase 1-Bromo-4-chlorobutane, a direct inquiry to established manufacturers can yield competitive quotes and samples. Clearly stating your requirements, including desired purity, quantity, and intended application, will help the supplier provide the most accurate information. Seeking out 'Diamond Members' or 'Audited Suppliers' on B2B platforms can also offer an added layer of assurance regarding their business legitimacy and operational standards.

By focusing on these critical aspects, pharmaceutical buyers can effectively source 1-Bromo-4-chlorobutane, securing a vital component for their drug development and manufacturing pipelines. Partnering with a reputable manufacturer is key to achieving both quality and cost efficiency in your supply chain.