For procurement professionals in the pharmaceutical and fine chemical sectors, identifying reliable sources for critical intermediates is a continuous challenge. 10,11-Dihydro-5H-dibenz[b,f]azepine (CAS 494-19-9) stands out as a high-value intermediate, essential for the synthesis of important drugs. This guide is designed to assist B2B buyers in navigating the process of purchasing this compound, with a particular focus on sourcing from China, a global hub for chemical manufacturing.

The Strategic Importance of 10,11-Dihydro-5H-dibenz[b,f]azepine

With a molecular formula of C14H13N and CAS number 494-19-9, 10,11-Dihydro-5H-dibenz[b,f]azepine is recognized for its purity (typically 99%) and its role as a precursor in the pharmaceutical industry. It is instrumental in the production of anticonvulsant medications, such as Carbamazepine, which are vital for managing epilepsy and other neurological conditions. As demand for these drugs continues, the need for a consistent and high-quality supply of this intermediate becomes increasingly critical.

Why China for Sourcing?

China has emerged as a dominant force in global chemical manufacturing, offering a vast array of intermediates and raw materials. When seeking to buy 10,11-Dihydro-5H-dibenz[b,f]azepine, Chinese manufacturers provide several advantages:

  • Cost-Effectiveness: Chinese suppliers often offer competitive pricing due to economies of scale and efficient production processes, making it attractive for bulk purchases.
  • Extensive Production Capacity: The country boasts numerous chemical plants capable of producing large volumes of intermediates, ensuring supply chain stability for growing demands.
  • Developing Expertise: Many Chinese chemical companies have invested significantly in R&D and quality control, leading to improved product standards and reliability.

Key Considerations for Buyers

To ensure a successful procurement experience, B2B buyers should focus on several key aspects:

  1. Supplier Verification: Thoroughly vet potential manufacturers. Look for suppliers with established export licenses, relevant certifications (e.g., ISO), and positive customer testimonials. Requesting company profiles and production facility information is advisable.
  2. Quality Control and Purity: Always prioritize suppliers who can guarantee a minimum purity of 99% for 10,11-Dihydro-5H-dibenz[b,f]azepine. Requesting Certificates of Analysis (CoAs) for each batch is essential for quality assurance.
  3. Pricing and Payment Terms: Obtain quotes from multiple suppliers to compare pricing. Clarify payment terms, incoterms (FOB, CIF, etc.), and any potential volume discounts. Understanding the price per kilogram is crucial for budgeting.
  4. Lead Times and Logistics: Inquire about production lead times and shipping arrangements. Reliable delivery schedules are critical for maintaining seamless production cycles. Discuss transportation options, including air and sea freight.
  5. Technical Support: A good supplier will offer technical support, including safety data sheets (SDS) and any necessary regulatory documentation.

Navigating the Purchase Process

When you decide to purchase 10,11-Dihydro-5H-dibenz[b,f]azepine, the process typically involves requesting a quote, negotiating terms, and arranging for payment and shipping. Many suppliers facilitate this through online platforms or direct contact. For instance, searching for '10,11-Dihydro-5H-dibenz[b,f]azepine supplier China' will yield numerous options. Engaging with these manufacturers can provide direct access to product specifications, pricing, and sample availability for your R&D or production needs.

In summary, sourcing 10,11-Dihydro-5H-dibenz[b,f]azepine (CAS 494-19-9) from China offers significant advantages in terms of cost and availability. By employing a diligent approach to supplier selection and quality verification, procurement professionals can secure a dependable supply of this vital pharmaceutical intermediate, thereby supporting the production of critical medicines.