For professionals in the pharmaceutical and chemical industries, securing reliable sources for key intermediates is paramount. One such critical compound is 1,5,6,7-Tetrahydro-4H-indol-4-one, identified by CAS number 13754-86-4. This indole derivative serves as a vital building block in the synthesis of a wide array of complex molecules, including significant pharmaceutical agents. Understanding its properties and sourcing reliably is crucial for R&D scientists and procurement managers alike.

What is 1,5,6,7-Tetrahydro-4H-indol-4-one?

1,5,6,7-Tetrahydro-4H-indol-4-one is a heterocyclic organic compound that features an indole core with specific functional groups. Its chemical structure makes it an excellent precursor for further chemical modifications, particularly in the creation of other indole derivatives and more complex pharmaceutical intermediates. Its melting point typically ranges from 188-190°C, and it presents as a white to light yellow crystalline powder, indicating its solid state under standard conditions.

Key Applications in Pharmaceutical Synthesis

The primary value of 1,5,6,7-Tetrahydro-4H-indol-4-one lies in its role as a reactant in various synthetic pathways. It is notably used in the preparation of Psammopemmin A, a compound known for its antitumor activity. Furthermore, it acts as a reactant in C-H insertion reactions for synthesizing beta-ketoesters and tricyclic tetrahydrobenzindoles, as well as in the preparation of condensed pyrroloindoles through palladium-catalyzed intramolecular C-H bond functionalization. Its utility extends to the preparation of condensed pyrroloindoles and derivatives that act as inhibitors of guanylate cyclase. These diverse applications highlight its importance for companies engaged in drug discovery and development.

Where to Buy 1,5,6,7-Tetrahydro-4H-indol-4-one?

When looking to buy 1,5,6,7-Tetrahydro-4H-indol-4-one, it is essential to partner with a reputable manufacturer and supplier. Key considerations include product purity, consistency, reliable supply chain, and competitive pricing. As a leading chemical supplier, we specialize in providing high-quality pharmaceutical intermediates like 1,5,6,7-Tetrahydro-4H-indol-4-one to research institutions and manufacturing companies globally. We offer comprehensive product information, including CAS details and chemical properties, to facilitate informed purchasing decisions. Enquiries for bulk quantities and custom specifications are always welcome. We aim to be your go-to supplier for this critical intermediate, ensuring you get the best price and quality.

Sourcing Strategy for Procurement Managers

Procurement managers should prioritize suppliers who demonstrate strong quality control measures, offer transparent pricing, and maintain robust inventory levels. Engaging with manufacturers directly, particularly those based in China, can offer significant cost advantages and direct access to product expertise. It is advisable to request quotations and product samples to verify quality before committing to larger orders. Understanding the typical uses and synthesis routes associated with 1,5,6,7-Tetrahydro-4H-indol-4-one will help in accurately assessing supplier capabilities. By focusing on these aspects, procurement managers can secure a stable and cost-effective supply of this vital chemical intermediate.

In conclusion, 1,5,6,7-Tetrahydro-4H-indol-4-one (CAS 13754-86-4) is an indispensable compound for modern pharmaceutical research and development. Ensuring a secure and quality-assured supply is key to advancing scientific and commercial objectives. For those looking to purchase this intermediate, engaging with experienced manufacturers and suppliers is the most strategic approach.