For procurement managers and R&D scientists in the pharmaceutical and fine chemical industries, sourcing reliable chemical intermediates is paramount. One such crucial compound is 2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine, also known by its synonym 7-azaindoline, with CAS number 10592-27-5. This heterocyclic organic compound serves as a vital building block in the synthesis of a wide range of pharmaceuticals and is also instrumental in the development of diagnostic reagents. Understanding its properties, applications, and where to procure it from reputable manufacturers and suppliers is key to a streamlined R&D and production process.

Understanding 2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine

2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine is characterized by its unique bicyclic structure, containing both a pyrrole and a pyridine ring fused together. It typically presents as a white powder, with a melting point generally ranging between 78-83 °C. Its chemical formula is C7H8N2, and it has a molecular weight of approximately 120.15 g/mol. These fundamental properties are critical for chemists when designing synthesis routes and ensuring product compatibility in various formulations. The availability of this compound in high purity is essential for its use in advanced chemical synthesis, especially in the highly regulated pharmaceutical sector.

Key Applications in the Chemical Industry

The primary utility of 2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine lies in its role as a pharmaceutical intermediate. It is frequently employed in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas, including oncology, neurology, and infectious diseases. Its structural motif can be incorporated into molecules designed to interact with specific biological targets, making it a valuable scaffold in drug discovery. Beyond pharmaceuticals, this compound also finds application in the creation of diagnostic reagents, where precise chemical structures are needed for accurate testing and analysis. For companies looking to buy this intermediate, its versatility as a building block in organic synthesis further enhances its market demand.

Where to Buy: Sourcing from Manufacturers and Suppliers

For procurement professionals, identifying reliable manufacturers and suppliers is crucial. When you need to buy 2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine, it is advisable to look for suppliers who can guarantee consistent quality, purity, and stable supply chains. China has emerged as a significant hub for the manufacturing and export of fine chemicals, including pharmaceutical intermediates. Partnering with a Chinese manufacturer or supplier that adheres to international quality standards can offer significant advantages in terms of cost-effectiveness and accessibility. When requesting a quote or inquiring about price, it is important to specify the required quantity and purity levels. Many suppliers will provide detailed product specifications, Certificates of Analysis (CoA), and Material Safety Data Sheets (MSDS) upon request. These documents are vital for quality control and regulatory compliance.

Factors to Consider for Your Purchase

When you are ready to purchase 2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine, consider the following:

  • Purity Level: Ensure the purity meets your specific application requirements, often 97% or higher for pharmaceutical use.
  • Supplier Reputation: Choose suppliers with a proven track record of quality and reliability.
  • Lead Times and Shipping: Understand the delivery times and shipping conditions, especially for international orders.
  • Regulatory Compliance: Verify that the supplier can provide necessary documentation for your region's regulations.

By focusing on these aspects, procurement managers can confidently secure a consistent supply of 2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine, supporting their company's innovation and production goals. Engaging with dedicated chemical manufacturers and distributors in China offers a strategic advantage in obtaining this essential chemical intermediate.