For researchers and procurement managers in the pharmaceutical and fine chemical industries, sourcing high-quality intermediates is paramount. 2,4-Difluoro-5-nitrobenzonitrile (CAS: 67152-20-9) stands out as a critical compound, particularly for its role in the synthesis of advanced therapeutic agents. Understanding its properties and identifying reliable suppliers are the first steps toward successful procurement and project execution.

This specialized chemical, often appearing as a light yellow powder, possesses a unique molecular structure that makes it invaluable in complex organic synthesis. Its molecular formula is C7H2F2N2O2, with a molecular weight of 184.100. Key physical properties include a density of approximately 1.5 g/cm³ and a boiling point around 271.5 °C. These characteristics ensure its stability and manageability under standard laboratory and industrial conditions.

The primary application that drives the demand for 2,4-Difluoro-5-nitrobenzonitrile is its function as a key building block in the synthesis of potent and selective tankyrase inhibitors. These inhibitors are crucial in modern cancer research, specifically for their ability to inhibit tumorigenesis – the process by which normal cells are transformed into cancerous cells. The presence of fluorine atoms in the molecule often enhances the efficacy and selectivity of the final drug product, making this intermediate highly sought after by pharmaceutical companies and contract research organizations (CROs).

When seeking to buy 2,4-Difluoro-5-nitrobenzonitrile, it is essential to prioritize purity and consistent quality. Manufacturers in China have become a significant global source for such intermediates, offering competitive pricing and robust production capabilities. A reputable manufacturer in China will guarantee an assay purity of ≥98.0%, ensuring that the compound performs as expected in sensitive synthesis routes. Look for suppliers who can provide detailed specifications, safety data sheets (SDS), and certificates of analysis (CoA) with every batch.

The supply chain for these specialized chemicals is becoming increasingly integrated, with numerous companies specializing in pharmaceutical intermediates. Procurement managers should look for suppliers who not only offer competitive prices but also demonstrate strong quality control measures and efficient logistics. The ability to provide technical support or custom packaging solutions can also be a deciding factor for large-scale industrial use. Engaging with a trusted 2,4-Difluoro-5-nitrobenzonitrile supplier means securing a reliable component for your R&D and manufacturing needs.

As research into cancer therapeutics continues to evolve, the demand for high-quality intermediates like 2,4-Difluoro-5-nitrobenzonitrile is expected to grow. By understanding the product's critical role and identifying trustworthy sources, organizations can confidently advance their drug discovery programs and contribute to breakthroughs in medical science. For those requiring this vital chemical, exploring options from established manufacturers in China offers a strategic advantage.