For procurement managers and R&D scientists in the chemical and pharmaceutical industries, sourcing high-quality intermediates is paramount. 2-Amino-3,5-difluorobenzoic Acid (CAS 126674-78-0) stands out as a valuable building block, particularly for its role in advanced synthesis. This article serves as a practical guide for those looking to buy this essential compound, focusing on key considerations when partnering with manufacturers and suppliers, especially those based in China.

Understanding the Compound: Properties and Significance

2-Amino-3,5-difluorobenzoic Acid is characterized by its difluorinated aromatic ring and the presence of both amine and carboxylic acid functional groups. Typically appearing as a yellow powder, its chemical formula is C7H5F2NO2, with a molecular weight of approximately 173.12 g/mol. Its purity, often specified as >95%, is a critical factor for its application in sensitive syntheses. The presence of fluorine atoms can impart unique properties to the final products, such as increased thermal stability, altered electronic properties, and enhanced biological activity, making it a sought-after intermediate in fields like advanced materials and pharmaceuticals.

Key Applications Driving Demand

The demand for 2-Amino-3,5-difluorobenzoic Acid is driven by its versatility. It serves as a crucial intermediate in the synthesis of:

  • Polymers: Particularly in the development of high-performance polymers like polyimides, where its structure contributes to enhanced thermal and chemical resistance.
  • Pharmaceuticals: As a building block for synthesizing active pharmaceutical ingredients (APIs) and complex organic molecules with potential therapeutic applications. Its fluorinated structure can influence drug metabolism and efficacy.
  • Agrochemicals: While not explicitly detailed in the reference materials, fluorinated aromatic compounds are often employed in the development of new agrochemicals due to their stability and biological activity.

Procurement Strategy: Finding Reliable Manufacturers and Suppliers

When you need to buy 2-amino-3,5-difluorobenzoic acid, identifying a dependable manufacturer and supplier is crucial. China has emerged as a significant hub for fine chemical production, offering competitive pricing and a broad range of products. Key considerations for selecting a supplier include:

  • Purity and Quality Assurance: Always verify the product's purity specifications (e.g., >95%) and inquire about quality control measures and certificates of analysis (CoA). Manufacturers with robust quality management systems are essential for consistent results.
  • Supply Chain Reliability: For ongoing projects, ensuring a stable supply is vital. Look for suppliers with substantial stock levels and efficient production capacities. Companies offering custom synthesis can also be beneficial for specific project requirements.
  • Technical Support and Communication: A responsive supplier with strong technical knowledge can assist with product inquiries, application advice, and troubleshooting. Clear communication channels are key to a successful partnership.
  • Pricing and Packaging: Compare pricing across different suppliers, but always balance cost with quality and reliability. Understand the available packaging options (e.g., grams to kilograms) to suit your research or production scale.

Navigating the Market: Where to Buy

Several chemical suppliers specialize in providing research chemicals and intermediates. When searching for a supplier of 2-amino-3,5-difluorobenzoic acid in China, it is advisable to consult industry directories, online chemical marketplaces, and directly contact potential manufacturers. These platforms often provide detailed product information, including CAS numbers, physical properties, safety data sheets (SDS), and supplier contact details. Requesting a free sample can also be a prudent step before committing to larger orders.

Conclusion

2-Amino-3,5-difluorobenzoic Acid (CAS 126674-78-0) is a valuable compound for chemists and material scientists. By understanding its properties, applications, and adopting a strategic procurement approach, businesses can effectively source this intermediate from reliable manufacturers. Prioritizing quality, reliability, and clear communication will ensure the success of your R&D and production initiatives. If you are looking to purchase this chemical, consider contacting established Chinese chemical suppliers for competitive pricing and dependable service.