For professionals in the pharmaceutical and fine chemical industries, securing a reliable supply of high-quality intermediates is paramount. One such critical compound is 2-Chloro-3,5-dinitropyridine, known by its CAS number 2578-45-2. This article serves as a comprehensive guide for procurement managers and R&D scientists looking to buy this essential chemical, focusing on key considerations like purity, supplier reputation, and cost-effectiveness.

Understanding 2-Chloro-3,5-dinitropyridine (CAS 2578-45-2)

2-Chloro-3,5-dinitropyridine is a vital pyridine derivative extensively used as a building block in organic synthesis, particularly for pharmaceutical intermediates. Its molecular structure, featuring a chlorinated pyridine ring substituted with two nitro groups, makes it a versatile reactant for various chemical transformations. Typically appearing as a white to light yellow powder, its physical properties and chemical reactivity are well-documented, with common purity levels exceeding 98%.

Key Factors When Sourcing This Intermediate

When you need to buy 2-chloro-3,5-dinitropyridine, several factors should guide your selection process:

  • Purity is Paramount: For pharmaceutical synthesis and sensitive R&D applications, a high purity level (≥98% or ≥98.0% by HPLC/GC) is non-negotiable. Impurities can significantly affect reaction yields, product quality, and downstream processes. Always inquire about the specific analytical methods used for quality control.
  • Supplier Reliability: Identifying a dependable manufacturer and supplier, especially one based in China known for its robust chemical industry, is crucial. Look for suppliers with established quality management systems (like ISO certification), consistent production capabilities, and transparent communication channels. Building a relationship with a trusted supplier ensures continuity of supply, which is vital for maintaining production schedules.
  • Pricing and Packaging: While quality is key, competitive pricing is also a significant consideration for procurement managers. Obtaining quotes from multiple suppliers can help determine market value. Additionally, inquire about packaging options (e.g., aluminum foil bags, 25kg drums) to ensure suitability for your storage and handling requirements.
  • Technical Support and Documentation: A good supplier will offer comprehensive technical documentation, including Certificates of Analysis (COA) for specific batches, Safety Data Sheets (SDS), and responsive technical support. This assistance can be invaluable when troubleshooting or optimizing synthesis pathways.

Navigating the Market: Manufacturer vs. Distributor

When sourcing 2-chloro-3,5-dinitropyridine, you might encounter both manufacturers and distributors. Purchasing directly from a manufacturer often provides better pricing and more direct control over quality and supply chain specifics. However, distributors can offer advantages in terms of smaller order quantities, faster delivery for readily available stock, and consolidated purchasing options.

Why Choose a Chinese Manufacturer?

China has emerged as a global hub for chemical manufacturing, offering competitive advantages in production scale, technological advancement, and cost efficiency. For intermediates like CAS 2578-45-2, partnering with a reputable Chinese manufacturer can provide access to high-quality materials at attractive price points. NINGBO INNO PHARMCHEM CO.,LTD. is committed to being that trusted partner, ensuring you receive the purity and reliability you need for your critical applications. We welcome inquiries for bulk purchases and long-term supply agreements.

Conclusion

Sourcing 2-chloro-3,5-dinitropyridine requires a careful evaluation of purity, supplier credibility, and commercial terms. By understanding these factors and partnering with experienced manufacturers, R&D professionals can ensure the success of their synthesis projects. We encourage you to reach out for a quote and discuss how we can meet your specific needs for this essential chemical intermediate.