For procurement managers and R&D scientists in the pharmaceutical sector, identifying reliable sources for critical intermediates is paramount. One such compound, 2-Chloro-4-(difluoromethoxy)pyridine (CAS: 1206978-15-5), plays a significant role in advanced organic synthesis for Active Pharmaceutical Ingredients (APIs). Understanding how to effectively buy this compound involves a careful assessment of its specifications and the capabilities of its manufacturers.

Understanding the Product: Purity and Specifications

When looking to purchase 2-Chloro-4-(difluoromethoxy)pyridine, key specifications to consider include its molecular formula (C6H4ClF2NO), molecular weight (179.55), and, crucially, its purity. Typically offered at 97% purity, this ensures that the intermediate meets the stringent requirements for pharmaceutical applications. Its physical state as a colorless liquid, along with its flash point (80.1±25.9 °C) and boiling point (208.8±35.0 °C at 760 mmHg), provides vital handling and storage information. Proper storage, often recommended under inert gas at 2-8°C, is essential to maintain its integrity.

Finding Reliable Suppliers in China

China has emerged as a leading global hub for chemical manufacturing, including specialized pharmaceutical intermediates. For buyers seeking 2-Chloro-4-(difluoromethoxy)pyridine, partnering with a reputable Chinese supplier can offer significant advantages in terms of cost-effectiveness and availability. Look for manufacturers who demonstrate a strong commitment to quality control, offer detailed Certificates of Analysis (CoA), and can provide consistent supply for both R&D and commercial-scale needs. The ability to offer free samples for initial evaluation is also a strong indicator of a supplier's confidence in their product.

Key Considerations for Procurement

When engaging with potential suppliers for 2-Chloro-4-(difluoromethoxy)pyridine, several factors should be prioritized:

  • Pricing: Request quotes from multiple manufacturers to secure the best possible price. Consider bulk discounts for larger orders.
  • Lead Times: Understand the production and shipping lead times, especially if you have a time-sensitive project. A reliable manufacturer will provide realistic estimates.
  • Quality Assurance: Inquire about their quality control processes and certifications to ensure the product consistently meets your specifications.
  • Technical Support: A good supplier will offer technical support to assist with any questions regarding product application or handling.

By thoroughly evaluating these aspects, procurement professionals can confidently source 2-Chloro-4-(difluoromethoxy)pyridine, ensuring their pharmaceutical development projects are supported by high-quality intermediates from dependable Chinese manufacturers.