For professionals in the pharmaceutical and fine chemical industries, sourcing high-quality intermediates is paramount to successful product development and manufacturing. Among these critical compounds, 2-Chlorophenothiazine (CAS 92-39-7) stands out due to its significant role in various synthetic pathways, most notably as a metabolite of the widely used drug Chlorpromazine.

Understanding the importance of reliable sourcing, this article delves into why 2-Chlorophenothiazine is a sought-after chemical and what factors B2B procurement managers and research scientists should consider when looking to purchase this compound. We will explore its properties, applications, and how to ensure a stable supply from reputable manufacturers.

What is 2-Chlorophenothiazine?

2-Chlorophenothiazine is an organic compound with the molecular formula C12H8ClNS and CAS number 92-39-7. It typically appears as a pale beige to beige solid and possesses a melting point in the range of 199-200°C. Its chemical structure, featuring a phenothiazine core with a chlorine atom substitution, makes it a versatile building block in organic synthesis. The compound is recognized as a metabolite of Chlorpromazine, an antipsychotic medication, making it valuable for pharmaceutical research and quality control as an impurity standard.

Key Applications in Industry

The primary utility of 2-Chlorophenothiazine lies in its function as a chemical intermediate. Its specific structure allows it to participate in a variety of reactions, facilitating the synthesis of more complex molecules. Key application areas include:

  • Pharmaceutical Synthesis: It serves as a crucial precursor or intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). Its use is vital for creating specific drug compounds, contributing to the development of novel therapeutics or generic medications.
  • Chemical Research and Development: R&D scientists utilize 2-Chlorophenothiazine for exploring new synthetic routes, investigating reaction mechanisms, and developing novel compounds with potential applications in materials science, agrochemicals, or specialty chemicals.
  • Impurity Profiling and Reference Standards: Given its relationship with Chlorpromazine, 2-Chlorophenothiazine is an important reference standard for analytical laboratories. It is used to identify and quantify impurities in pharmaceutical products, ensuring compliance with regulatory standards and product safety.

Ensuring a Reliable Supply

For businesses relying on a steady influx of 2-Chlorophenothiazine, selecting the right manufacturer and supplier is critical. When you buy 2-Chlorophenothiazine, consider the following:

  • Purity and Quality: Look for suppliers who provide detailed Certificates of Analysis (CoA) specifying purity levels (e.g., >95% or >98% by HPLC/GC) and adhering to stringent quality control measures.
  • Manufacturer Reputation: Partner with established manufacturers known for their consistent quality, production capacity, and ethical business practices. Sourcing from a reputable manufacturer ensures that your intermediates meet the required specifications.
  • Supply Chain Stability: A reliable supplier will have a robust production and logistics network to ensure timely delivery, preventing disruptions to your manufacturing schedules. Consider suppliers who offer flexible order quantities, from grams for R&D to kilograms for bulk production.
  • Competitive Pricing: Obtain price quotes from multiple suppliers to ensure you are getting the best value for your investment. However, prioritize quality and reliability over the lowest price alone.

NINGBO INNO PHARMCHEM CO.,LTD. is a premier manufacturer and supplier of fine chemical intermediates, including 2-Chlorophenothiazine. We are dedicated to providing our clients with superior quality products, competitive pricing, and a dependable supply chain. Our commitment to excellence makes us an ideal partner for your pharmaceutical synthesis and chemical research needs. If you are looking to purchase 2-Chlorophenothiazine or require a detailed price quote, we encourage you to contact us.