In the dynamic world of pharmaceutical research and development, the procurement of high-quality chemical intermediates is paramount. One such crucial compound is 2-Fluoro-3-iodo-6-methylpyridine, identified by its CAS number 884494-48-8. As a specialized fine chemical, its availability from reliable manufacturers and suppliers significantly impacts the efficiency and success of drug synthesis. This article aims to guide pharmaceutical procurement managers and R&D scientists in understanding the importance of this intermediate and how to best source it.

Understanding 2-Fluoro-3-iodo-6-methylpyridine: Properties and Applications

2-Fluoro-3-iodo-6-methylpyridine is a fluorinated pyridine derivative, a class of compounds highly valued for their unique electronic and steric properties. These characteristics make them indispensable building blocks in the synthesis of complex organic molecules, particularly within the pharmaceutical industry. Its specific structure, featuring fluorine and iodine substituents on a methylpyridine core, allows for diverse chemical transformations, enabling the creation of novel drug candidates and active pharmaceutical ingredients (APIs). Beyond pharmaceuticals, this compound also finds utility in the cosmetics industry due to its specific chemical properties.

For procurement professionals, understanding the required purity is crucial. Typically, pharmaceutical applications demand intermediates with purity levels of 98% or higher to ensure the efficacy and safety of the final drug product. Reliable manufacturers will provide detailed Certificates of Analysis (CoA) to verify these specifications, often detailing properties like appearance (commonly a white powder), molecular formula (C6H5FIN), and molecular weight (237.01 g/cm³). Its boiling point of 233.1 °C at 760 mmHg is also a key physical parameter.

Key Considerations for Pharmaceutical Buyers: Sourcing from China Manufacturers and Suppliers

When seeking to purchase 2-Fluoro-3-iodo-6-methylpyridine, identifying a dependable China manufacturer and supplier is a strategic advantage. The Chinese chemical market offers competitive pricing and a vast production capacity, making it an attractive source for global procurement. However, diligence in supplier selection is essential.

  • Quality Assurance: Prioritize manufacturers who adhere to strict quality control protocols and can consistently supply the required purity levels. Look for ISO certifications or other quality management system accreditations.
  • Supply Chain Stability: For ongoing projects, ensuring a stable supply chain is critical. Manufacturers with robust production capabilities and established logistics are preferred. This includes reliable shipping options via ocean, land, or air, with key ports like Shanghai and Qingdao being common export hubs.
  • Competitive Pricing: As a buyer, obtaining a competitive price for 2-Fluoro-3-iodo-6-methylpyridine is a significant factor. Direct relationships with manufacturers often yield better pricing than dealing with multiple intermediaries. Inquire about bulk order discounts and flexible payment terms (e.g., T/T, L/C, PayPal).
  • Technical Support and Documentation: A good supplier will provide comprehensive technical data, including MSDS (Material Safety Data Sheet) and detailed product specifications. Responsive customer service and efficient inquiry handling are also indicators of a reliable partner.

Navigating the Purchase Process

When engaging with a potential manufacturer for 2-Fluoro-3-iodo-6-methylpyridine, be prepared to discuss your specific needs. This includes the required quantity (ranging from grams for R&D to metric tons for commercial production), desired packaging, and delivery timelines. Requesting a quote for your required 884494-48-8 purchase is the first step. Many suppliers offer samples for evaluation, which is an excellent way to confirm product quality before committing to larger orders. Remember to clarify incoterms (e.g., FOB, CIF, EXW) to understand shipping responsibilities and costs.

Conclusion

Securing a consistent and high-quality supply of 2-Fluoro-3-iodo-6-methylpyridine is vital for pharmaceutical companies. By understanding the product's properties and meticulously selecting a reputable China manufacturer and supplier, procurement managers can ensure the seamless progress of their research and production pipelines. For your next requirement of this critical intermediate, consider partnering with a trusted supplier in China to achieve both quality and cost-efficiency in your purchase.