For procurement managers in the pharmaceutical sector, sourcing high-quality intermediates is paramount. 2-Fluoroisonicotinic Acid, identified by CAS number 402-65-3, stands out as a critical building block in the synthesis of numerous Active Pharmaceutical Ingredients (APIs) and other specialized organic compounds. Understanding its properties and where to buy it effectively is key to streamlining your supply chain and ensuring product integrity.

What is 2-Fluoroisonicotinic Acid?

This chemical compound, with the molecular formula C6H4FNO2 and a molecular weight of 141.10, typically presents as a white to light yellow crystal powder. Its physical properties, such as a melting point of 200 °C (with decomposition), are important considerations for handling and storage. As a pharmaceutical intermediate, its primary role is to facilitate the creation of more complex molecules used in drug development. Its structural features make it particularly valuable in the synthesis of fluorinated compounds, a class of materials increasingly important in medicinal chemistry due to fluorine's unique ability to modulate a molecule's metabolic stability, lipophilicity, and binding affinity.

Key Applications in Pharmaceutical Development

The versatility of 2-Fluoroisonicotinic Acid extends across various stages of pharmaceutical research and production. It serves as a crucial starting material for the synthesis of pyridine derivatives, which are common scaffolds in many therapeutic agents. Researchers and formulators actively seek this compound when developing new treatments, making it a highly sought-after R&D chemical. The demand for reliable suppliers who can consistently deliver this intermediate with high purity is therefore constant. When you buy 2-Fluoroisonicotinic Acid, you are investing in a foundational component for innovation.

Navigating the Procurement Process

When procuring 2-Fluoroisonicotinic Acid, procurement professionals should focus on key specifications: purity (often required at ≥98.0%), appearance, and reliable CAS number identification (402-65-3). It is also beneficial to identify manufacturers and suppliers who can provide comprehensive documentation, such as Certificates of Analysis (CoA) and Safety Data Sheets (SDS). For many businesses, sourcing from established manufacturers in China offers a competitive advantage in terms of both price and availability. Companies like NINGBO INNO PHARMCHEM CO.,LTD. are dedicated to providing such high-quality intermediates, ensuring that your procurement process is efficient and your final products meet rigorous pharmaceutical standards.

By understanding the critical role of 2-Fluoroisonicotinic Acid and partnering with reputable suppliers, pharmaceutical companies can ensure a robust supply of essential materials for their drug discovery and manufacturing pipelines. This strategic approach to sourcing intermediates like CAS 402-65-3 is fundamental to bringing life-saving medications to market.