In the intricate world of pharmaceutical development, the quality and reliability of starting materials are paramount. One such compound that plays a significant role is 2'-Hydroxypropiophenone, identified by its CAS number 610-99-1. This aromatic ketone is far more than just a chemical entity; it's a critical building block that empowers scientists to synthesize complex molecules with potential therapeutic benefits. For procurement managers and R&D professionals, understanding the value and sourcing of this intermediate is key to advancing drug discovery pipelines.

What is 2'-Hydroxypropiophenone?

2'-Hydroxypropiophenone, chemically known as 1-(2-hydroxyphenyl)propan-1-one, is characterized by a propiophenone structure with a hydroxyl group positioned ortho to the carbonyl group on the phenyl ring. This specific arrangement of functional groups bestows upon it unique reactivity, making it an exceptionally versatile synthon. Its typical appearance is a colorless to pale yellow transparent liquid, with a purity of 97% minimum, ensuring consistent performance in sensitive chemical processes.

The Crucial Role in Pharmaceutical Synthesis

The primary significance of 2'-Hydroxypropiophenone lies in its function as a key intermediate for the stereoselective synthesis of vicinal diols. A prominent example is the production of 1-phenylpropane-1,2-diol (PPD), which serves as a versatile building block for various pharmaceutical agents. The ability to precisely control the stereochemistry of these diols is vital for developing drugs with targeted efficacy and minimized side effects. Furthermore, its derivatives are instrumental in the synthesis of compounds with potential neurological applications, underscoring its importance in drug discovery.

Beyond Pharmaceuticals: A Versatile Organic Synthesis Tool

While its pharmaceutical applications are substantial, 2'-Hydroxypropiophenone is also a prized compound in general organic chemistry. Its aromatic α-hydroxy ketone structure makes it a highly sought-after chiral building block. Researchers utilize it for creating more complex molecular architectures, including those found in natural products and novel materials. The reactivity of its functional groups allows for further modifications, leading to a diverse array of derivatives with unique properties. For instance, it can be used to synthesize Schiff bases and their metal complexes, which have been investigated for antimicrobial activities.

Sourcing High-Quality 2'-Hydroxypropiophenone from China

For procurement managers seeking a reliable supplier in China for 2'-Hydroxypropiophenone, consistency in quality and competitive pricing are paramount. Leading chemical manufacturers in China offer this compound with stringent quality controls, ensuring the 97% minimum purity required for advanced synthesis. When looking to buy this essential intermediate, partnering with a reputable manufacturer provides access to both high-grade products and potential cost savings. Inquiry for a quote is the first step towards securing a dependable supply chain for your R&D projects.

In conclusion, 2'-Hydroxypropiophenone (CAS 610-99-1) stands as a testament to the power of fine chemical intermediates in driving innovation. Whether for cutting-edge pharmaceutical development or intricate organic synthesis, this compound offers a robust foundation. By understanding its applications and securing it from trusted sources, researchers can continue to push the boundaries of what is chemically possible.