For procurement managers and R&D scientists in the pharmaceutical sector, sourcing reliable and high-purity chemical intermediates is paramount. Among these critical compounds is 2'-Iodoacetophenone (CAS 2142-70-3), a versatile building block widely employed in the synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules. This guide aims to equip you with the knowledge to effectively buy 2'-Iodoacetophenone, focusing on what to look for when selecting a manufacturer and ensuring the quality you need for your synthesis.

Understanding 2'-Iodoacetophenone (CAS 2142-70-3)

2'-Iodoacetophenone, with its characteristic structure of an acetophenone substituted with an iodine atom at the ortho position, serves as a key intermediate in numerous chemical reactions. Its molecular formula is C8H7IO, and it is often described as a clear yellow liquid with a high purity, typically 99% minimum. The chemical's utility lies in its reactivity, enabling the creation of intricate molecular structures vital for drug discovery and development. For instance, it plays a role in the synthesis of indene derivatives and other bioactive compounds, making it a sought-after reagent in medicinal chemistry.

Key Considerations for Sourcing

When looking to purchase 2'-Iodoacetophenone, several factors should guide your decision-making process:

  • Purity Levels: For pharmaceutical applications, ultra-high purity is non-negotiable. Ensure the manufacturer clearly states the purity of their 2'-Iodoacetophenone, typically specified as 98% or 99% minimum. Certificates of Analysis (CoA) should be readily available to verify these claims.
  • Supplier Reliability: Identifying a trustworthy manufacturer or supplier is crucial. Look for companies with a strong track record in producing and exporting pharmaceutical intermediates. Consider factors like production capacity, quality control systems, and adherence to international standards. Working with a reputable supplier in China can offer competitive pricing and efficient logistics.
  • Technical Specifications: Familiarize yourself with the product's physical and chemical properties, including its appearance (clear yellow liquid), boiling point, density, and refractive index. These details are essential for process optimization and quality assurance.
  • Packaging and Handling: Proper packaging is vital for maintaining the integrity of 2'-Iodoacetophenone during transit and storage. Common packaging includes amber glass bottles or aluminum foil bags, often in quantities ranging from grams to kilograms, to suit various research and production scales.
  • Pricing and Availability: Obtaining a quote for 2'-Iodoacetophenone is a necessary step. Compare prices from different suppliers while considering the overall value proposition, including quality, service, and delivery timelines. Understanding the supplier's inventory and lead times for bulk orders is also important.

The Role of Manufacturers in China

China has emerged as a significant hub for chemical manufacturing, offering competitive pricing and extensive production capabilities. When you buy 2'-Iodoacetophenone from a Chinese manufacturer, you can often leverage cost efficiencies without compromising on quality, provided you partner with a reputable entity. These suppliers are experienced in international trade and can facilitate smooth transactions and timely deliveries to global destinations.

Initiating Your Purchase

To secure your supply of 2'-Iodoacetophenone, reach out to established manufacturers and suppliers. Clearly state your requirements, including the desired purity, quantity, and delivery schedule. Don't hesitate to request samples for evaluation before committing to larger orders. By prioritizing these aspects, you can ensure you procure high-quality 2'-Iodoacetophenone that meets the exacting standards of the pharmaceutical industry.

For those seeking a dependable source, consider exploring partnerships with established chemical suppliers who specialize in pharmaceutical intermediates. They can provide the quality, consistency, and service necessary to support your critical synthesis projects.