For procurement managers and R&D scientists in the chemical industry, sourcing high-quality intermediates is paramount. 3,5-Difluoroanisole (CAS 93343-10-3) stands out as a crucial building block, particularly for sectors like pharmaceuticals and agrochemicals. Understanding where to buy, what to look for in terms of purity, and how pricing works is essential for making informed purchasing decisions. This article aims to guide you through the process of acquiring 3,5-Difluoroanisole from reliable manufacturers and suppliers.

Understanding 3,5-Difluoroanisole

3,5-Difluoroanisole is a fluorinated aromatic ether, characterized by its colorless to pale yellow liquid appearance and a molecular formula of C7H6F2O. Its significance lies in its utility as an intermediate in complex organic syntheses. The presence of fluorine atoms on the benzene ring imparts unique electronic properties, making it highly valuable for creating molecules with enhanced stability, specific reactivity, and improved bioavailability or efficacy in their final applications.

Its primary applications include:

  • Pharmaceutical Intermediates: Crucial for synthesizing active pharmaceutical ingredients (APIs) where fluorination can improve metabolic stability, lipophilicity, and target binding.
  • Agrochemical Synthesis: Used in the development of pesticides and herbicides, where fluorine incorporation can lead to more potent and environmentally stable compounds.
  • Material Science: Applied in the creation of specialty chemicals, liquid crystals, and electronic materials due to its distinct chemical and physical properties.

Key Considerations When Sourcing

When looking to buy 3,5-Difluoroanisole, several factors are critical:

  • Purity: For most applications, especially in pharmaceuticals, a high purity level, typically ≥98%, is non-negotiable. This ensures the success of downstream reactions and the quality of the final product. Always request a Certificate of Analysis (COA) to verify the purity and specifications.
  • Supplier Reliability: Partnering with a reputable manufacturer or supplier is key. Look for companies with a proven track record, certifications, and transparent communication. Suppliers offering custom synthesis and contract manufacturing services can also be valuable for specific project needs.
  • Pricing and Quotation: Chemical prices are subject to market fluctuations. While online listings may provide indicative prices (e.g., around US$2.50/kg for bulk quantities), it's always best to request a formal quote. Factors influencing price include order volume, packaging, and delivery terms. Manufacturers based in China often provide competitive pricing for intermediates like 3,5-Difluoroanisole.
  • Lead Times and Delivery: Understand the lead times for production and delivery. Reliable suppliers will offer clear timelines and efficient logistics to ensure your project stays on track.

Finding a Manufacturer or Supplier

Numerous chemical suppliers and manufacturers offer 3,5-Difluoroanisole. When searching, use terms like “3,5-Difluoroanisole manufacturer,” “buy 3,5-Difluoroanisole CAS 93343-10-3,” or “3,5-Difluoroanisole supplier China.” Companies specializing in fine chemicals and pharmaceutical intermediates are your best bet. Prioritize those who provide comprehensive technical support, MSDS (Material Safety Data Sheets), and have established export experience.

By carefully evaluating these aspects, procurement professionals can secure a dependable supply of high-quality 3,5-Difluoroanisole, driving innovation and success in their respective fields. Contacting us for a quote or sample is the first step towards securing this vital chemical intermediate for your operations.