Sourcing 3-Bromo-5-chloropyridine: A Guide for Procurement Managers
For procurement managers in the chemical, pharmaceutical, and agrochemical industries, securing a consistent and high-quality supply of essential intermediates is a critical function. 3-Bromo-5-chloropyridine (CAS: 73583-39-8) is one such intermediate, valued for its versatile reactivity and broad applicability in complex organic synthesis. Understanding its industrial importance, typical specifications, and where to source it effectively is key to streamlining supply chains and ensuring project success. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. play a crucial role in meeting this demand.
The industrial significance of 3-Bromo-5-chloropyridine stems from its unique chemical structure, featuring a bromine atom at the 3-position and a chlorine atom at the 5-position of the pyridine ring. This di-halogenated motif provides chemists with a powerful tool for selective functionalization. In synthetic routes, the differential reactivity of the carbon-bromine versus the carbon-chlorine bond allows for precise control over chemical transformations. For instance, the bromine atom is more readily involved in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura coupling, enabling the regioselective introduction of various organic fragments. This makes it an ideal building block for pharmaceuticals and agrochemicals where specific molecular architectures are required.
Key applications for this intermediate include the synthesis of active pharmaceutical ingredients (APIs) and agrochemical active ingredients. In pharmaceuticals, derivatives of 3-Bromo-5-chloropyridine are explored for their potential therapeutic effects, ranging from anti-inflammatory agents to compounds for neurological disorders. In the agrochemical sector, it is vital for creating effective pesticides and herbicides. Its role as a versatile starting material for further chemical modifications makes it a high-demand product for research and development as well as large-scale manufacturing.
When procuring 3-Bromo-5-chloropyridine, procurement managers should look for suppliers who can provide material with a high purity, typically specified as ≥99.0% by High-Performance Liquid Chromatography (HPLC). This ensures the reliability and reproducibility of synthetic processes. Additionally, understanding the physical properties, such as its appearance (usually a white to tan solid) and the recommended storage conditions (cool, ventilated place), is important for effective inventory management and material handling. Sourcing from a manufacturer in China that offers competitive pricing and a stable supply chain is often a strategic advantage.
For companies requiring this essential chemical intermediate, partnering with a reputable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to quality-assured products. Their commitment to providing high-purity 3-Bromo-5-chloropyridine, backed by comprehensive technical specifications, supports seamless integration into existing manufacturing processes. By understanding the value and sourcing considerations for 3-Bromo-5-chloropyridine, procurement professionals can effectively meet the demands of innovation in the pharmaceutical and agrochemical industries.
Perspectives & Insights
Logic Thinker AI
“For procurement managers in the chemical, pharmaceutical, and agrochemical industries, securing a consistent and high-quality supply of essential intermediates is a critical function.”
Molecule Spark 2025
“3-Bromo-5-chloropyridine (CAS: 73583-39-8) is one such intermediate, valued for its versatile reactivity and broad applicability in complex organic synthesis.”
Alpha Pioneer 01
“Understanding its industrial importance, typical specifications, and where to source it effectively is key to streamlining supply chains and ensuring project success.”