For procurement managers and R&D scientists in the pharmaceutical and fine chemical industries, sourcing high-quality intermediates is paramount. 4-Amino-2-(trifluoromethyl)benzonitrile (CAS: 654-70-6) stands out as a critical building block, particularly for its role in synthesizing advanced therapeutic agents. This article aims to provide essential insights for buyers looking to secure a consistent and cost-effective supply of this vital compound.

Understanding the Product and Its Importance

4-Amino-2-(trifluoromethyl)benzonitrile is an organic compound recognized for its utility as a pharmaceutical intermediate. Its chemical structure, featuring both an amino group and a trifluoromethyl-substituted benzonitrile moiety, makes it an ideal precursor for a range of complex molecules. Notably, it plays a role in the synthesis of benzimidazoles, which are being investigated for their potential in treating breast cancer by inhibiting endothelial cell growth. Furthermore, it is utilized in preparing benzene derivatives that function as non-steroidal androgen receptor modulators, crucial in hormone therapy research. As a buyer, understanding these applications highlights the need for high purity and reliable specifications.

Key Considerations When Buying

When considering where to buy 4-Amino-2-(trifluoromethyl)benzonitrile, several factors should influence your decision. Firstly, purity is critical. Look for suppliers who clearly state their product's minimum purity (often 97% or higher) and can provide certificates of analysis (CoA). Secondly, supply chain reliability is essential. Partnering with a manufacturer or a reputable supplier in China can offer advantages in terms of production capacity and competitive pricing.

Navigating the Supplier Landscape

The global market features numerous manufacturers and suppliers of 4-Amino-2-(trifluoromethyl)benzonitrile. For businesses in North America and Europe, sourcing from China can often provide a significant cost advantage without compromising on quality, provided due diligence is performed. When searching for a supplier, utilize long-tail keywords such as 'buy 4-amino-2-(trifluoromethyl)benzonitrile in China,' '4-amino-2-(trifluoromethyl)benzonitrile supplier,' or 'CAS 654-70-6 price' to identify potential partners. Engage with manufacturers directly to inquire about product specifications, batch consistency, lead times, and minimum order quantities. Requesting a free sample is a standard practice to verify product quality before placing a bulk order.

Price and Bulk Purchasing

The price of 4-Amino-2-(trifluoromethyl)benzonitrile can vary based on purity, quantity, and the supplier. For bulk purchases, direct negotiation with manufacturers is often the most effective way to secure competitive pricing. Suppliers who can offer transparent pricing structures and flexible packaging options (e.g., 5g, 25g, 100g, 500g, or bulk) are generally preferred. Understanding the total landed cost, including shipping and any applicable duties, is crucial for accurate budgeting.

Conclusion

Securing a reliable supply of 4-Amino-2-(trifluoromethyl)benzonitrile is a strategic decision for any organization involved in pharmaceutical R&D or specialty chemical synthesis. By focusing on purity, supply chain stability, and competitive pricing, procurement professionals can effectively identify and partner with leading manufacturers and suppliers. For those seeking a trusted source, exploring options from China's established chemical industry can lead to significant advantages. If you are looking to purchase this intermediate, engaging with experienced manufacturers will ensure you meet your project's stringent requirements.