For professionals in the pharmaceutical and agrochemical industries, securing a consistent and high-quality supply of key intermediates is paramount. One such critical compound is 5-Chloro-2-hydroxypyridine (CAS 4214-79-3). This versatile heterocyclic building block plays a vital role in the synthesis of a wide range of advanced chemical products. Understanding where to buy and what to look for in a supplier can significantly impact your research and production efficiency.

Why 5-Chloro-2-hydroxypyridine is Essential

5-Chloro-2-hydroxypyridine, also known by synonyms like 5-Chloropyridin-2-ol or 5-Chloro-2-pyridone, is indispensable for several reasons. Its unique chemical structure, featuring both a chloro substituent and a hydroxyl group on a pyridine ring, makes it a highly reactive and versatile intermediate. It is a cornerstone in the synthesis of neonicotinoid insecticides, a class of compounds vital for modern agriculture and crop protection. Furthermore, its utility extends to the pharmaceutical sector, where it serves as a precursor for various Active Pharmaceutical Ingredients (APIs), including antiviral and antibacterial agents. Its potential as a ligand in material science also opens avenues for innovative applications.

Navigating the Purchase Process: Manufacturer vs. Distributor

When sourcing chemical intermediates like 5-Chloro-2-hydroxypyridine, you'll encounter both manufacturers and distributors. While distributors can offer convenience, purchasing directly from a manufacturer, especially one based in China, often yields significant advantages. Manufacturers can typically offer more competitive pricing due to reduced overheads and direct control over the production process. Moreover, direct relationships with manufacturers ensure better traceability, consistent quality control, and the ability to negotiate bulk purchase terms more effectively. When looking to buy 5-Chloro-2-hydroxypyridine, prioritize engaging with reputable manufacturers.

Ensuring Quality and Purity for Your Synthesis

The purity of 5-Chloro-2-hydroxypyridine is a critical factor that directly influences the success of your synthesis. Look for suppliers that provide detailed Certificates of Analysis (CoA), specifying parameters such as assay (typically ≥98.0%), melting point (around 163-165°C), and the absence of significant impurities. Off-white to slight yellow solid appearance is standard. A reliable supplier will also offer information on storage conditions and handling to maintain product integrity. For those seeking 5-chloro-2-hydroxypyridine for pharmaceutical synthesis, stringent adherence to quality standards is non-negotiable.

Finding Competitive Price and Reliable Supply in China

China has emerged as a global hub for chemical manufacturing, offering a vast landscape of suppliers for intermediates like 5-Chloro-2-hydroxypyridine. To find a competitive price, it's advisable to solicit quotes from multiple manufacturers. Consider factors beyond just the per-kilogram price, such as minimum order quantities, lead times, shipping costs, and payment terms. A long-term partnership with a dependable supplier in China can ensure a stable supply chain, mitigating risks of shortages and price volatility. When searching for '5-chloro-2-hydroxypyridine CAS 4214-79-3 supplier in China', focus on those with proven track records and strong customer testimonials.

In conclusion, procuring 5-Chloro-2-hydroxypyridine requires a strategic approach. By prioritizing direct engagement with manufacturers, focusing on quality assurance, and understanding the market dynamics for competitive pricing, businesses can secure this essential chemical intermediate to drive their innovation forward.