For procurement managers and R&D scientists in the chemical and pharmaceutical sectors, sourcing high-quality intermediates is paramount. The compound 5-Chloro-4-fluoro-1H-indole-2-carboxylic acid (CAS: 186446-26-4) is a critical building block in many organic synthesis pathways. Understanding its properties and how to source it effectively can significantly impact project timelines and success rates. This guide aims to assist procurement professionals in making informed decisions when looking to buy this essential chemical intermediate.

Understanding the Product: Key Specifications and Properties

When evaluating a supplier for 5-Chloro-4-fluoro-1H-indole-2-carboxylic acid, several key specifications are crucial. The product is typically described as a white powder, ensuring ease of handling and integration into various laboratory and industrial processes. Its purity is a vital indicator of quality; a minimum assay of ≥98.0% is standard for reliable synthetic outcomes. Physical properties, such as a density of 1.635 g/cm³ and a boiling point of 455.4°C at 760 mmHg, provide important context for its chemical behavior and handling. Its molecular formula (C9H5ClFNO2) and molecular weight (213.59300) are also fundamental data points for stoichiometric calculations in synthesis.

Applications in Organic Synthesis: Why it Matters

5-Chloro-4-fluoro-1H-indole-2-carboxylic acid serves as a vital intermediate in the synthesis of more complex organic molecules. Its indole core, combined with halogen substituents, makes it a versatile precursor for a wide range of applications, including but not limited to the development of pharmaceuticals, agrochemicals, and specialty fine chemicals. Researchers and formulators rely on intermediates like this to efficiently construct target molecules, accelerating innovation and product development cycles. By understanding the demand for such specialized intermediates, manufacturers can ensure consistent availability and quality.

Sourcing Strategies: Finding a Reliable Manufacturer in China

For businesses seeking to purchase 5-Chloro-4-fluoro-1H-indole-2-carboxylic acid, identifying a reputable manufacturer in China is often a strategic move. Chinese chemical manufacturers offer competitive pricing and significant production capacity, making them attractive partners for both small-scale research and large-scale industrial needs. When selecting a supplier, consider factors such as:

  • Quality Control: Ensure the manufacturer has robust quality control measures in place, including certifications and consistent assay results.
  • Supply Chain Reliability: Look for suppliers with a proven track record of timely delivery and consistent product availability.
  • Technical Support: A supplier that offers technical support and readily provides necessary documentation (like MSDS) is invaluable.
  • Customization Options: While standard packaging is often 25 kg/drum, inquire about custom packaging to meet specific project requirements.

Engaging directly with manufacturers or their authorized distributors is key to securing competitive pricing and understanding lead times. Exploring options for purchasing 5-Chloro-4-fluoro-1H-indole-2-carboxylic acid from a trusted China supplier can streamline your procurement process and contribute to the overall success of your projects.

Conclusion: Partnering for Synthesis Success

Securing a reliable source of high-quality 5-Chloro-4-fluoro-1H-indole-2-carboxylic acid is a critical step for any organization involved in advanced organic synthesis. By focusing on product specifications, understanding its applications, and strategically selecting your supplier, you can ensure the efficiency and success of your chemical development endeavors. As a key supplier of organic synthesis intermediates, we are dedicated to supporting your research and manufacturing needs.