For procurement managers and research scientists in the chemical and pharmaceutical industries, sourcing high-quality intermediates is paramount. 6-Bromonicotinic acid, a vital pyridine derivative with CAS number 6311-35-9, stands out as a cornerstone in the synthesis of complex organic molecules. As a leading manufacturer and supplier, understanding the critical factors involved in procuring this compound can significantly streamline your R&D and production processes.

When considering the purchase of 6-Bromonicotinic acid, purity is the foremost concern. Reputable suppliers, like NINGBO INNO PHARMCHEM CO.,LTD., typically offer this intermediate with an assay of 98% or higher, often confirmed via HPLC. This high purity level is essential for ensuring predictable reaction outcomes and minimizing by-product formation in sensitive synthesis pathways, particularly those leading to APIs (Active Pharmaceutical Ingredients) or advanced agrochemicals.

The synthetic route employed by a manufacturer can also impact the quality and cost-effectiveness. Common methods include regioselective bromination of nicotinic acid derivatives or oxidation of functionalized pyridine precursors. Understanding these pathways can help procurement specialists evaluate the reliability and efficiency of a supplier's manufacturing process. For instance, a robust supply chain from a manufacturer based in China ensures competitive pricing and consistent availability.

6-Bromonicotinic acid's utility is largely derived from its bifunctional nature. The bromine atom at the 6-position is an excellent leaving group for palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, which are fundamental for building carbon-carbon bonds in complex molecular architectures. Simultaneously, the carboxylic acid group can be readily converted into esters, amides, or other functionalities, offering chemists a versatile handle for further derivatization. This dual reactivity makes it an indispensable building block in medicinal chemistry for drug discovery and in agrochemical research for developing new crop protection agents.

When sourcing this critical intermediate, it is advisable to request Certificates of Analysis (CoA) and Safety Data Sheets (SDS) to verify specifications and handling procedures. Engaging with experienced suppliers who can provide technical support and reliable bulk quantities is key. For businesses looking to buy 6-Bromonicotinic acid, partnering with a dedicated manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. guarantees access to premium quality chemical intermediates, supported by a commitment to customer satisfaction and timely delivery. Explore your options and secure a dependable source for your chemical synthesis needs.