For procurement managers and R&D scientists in the pharmaceutical and fine chemical industries, identifying reliable sources for critical intermediates is paramount. Alpha-Cyclopentylmandelic Acid (CAS 427-49-6) is one such compound, playing a significant role in the synthesis of advanced therapeutic agents, particularly those targeting respiratory conditions and acting as muscarinic M3 receptor antagonists. This guide aims to provide insights for buyers looking to purchase this essential chemical.

Understanding Alpha-Cyclopentylmandelic Acid (CAS 427-49-6)

Alpha-Cyclopentylmandelic Acid is a carboxylic acid derivative with a cyclopentyl group attached to the alpha-carbon of mandelic acid. Its chemical structure (C13H16O3, MW: 220.26) makes it a valuable building block in organic synthesis. Typically appearing as a white to pale brown solid with a melting point between 144-150 °C, its purity is a key specification for its intended applications, often requiring an assay of 98% or higher.

Key Applications in Pharmaceutical Synthesis

The primary utility of Alpha-Cyclopentylmandelic Acid lies in its function as a pharmaceutical intermediate. It is specifically utilized in the synthesis of muscarinic M3 receptor antagonists, a class of drugs investigated for treating various respiratory complaints. Furthermore, it is recognized as an impurity of Glycopyrrolate, making it relevant for quality control and analytical standards in pharmaceutical manufacturing. Its role as an organic building block extends to broader chemical synthesis projects.

Navigating the Procurement Process

When seeking to buy Alpha-Cyclopentylmandelic Acid, buyers should prioritize manufacturers and suppliers who can guarantee high purity, consistent quality, and reliable supply chains. Key considerations include:

  • Manufacturer Reputation: Look for suppliers with established track records in producing fine chemicals and pharmaceutical intermediates. Companies offering detailed product specifications, COAs (Certificates of Analysis), and MSDS (Material Safety Data Sheets) are generally more trustworthy.
  • Supply Ability and Lead Times: Ensure the supplier can meet your required quantities, whether for R&D or large-scale production. Understanding lead times from manufacturers in China is crucial for project planning.
  • Pricing and Payment Terms: Obtaining quotes from multiple suppliers is advisable. Factors such as Incoterms (FOB, CIF, EXW) and payment options (T/T, L/C, PayPal) will influence the overall cost and transaction ease.
  • Regulatory Compliance: Verify that the manufacturer adheres to relevant quality standards (e.g., ISO certification) and that the product meets necessary regulatory requirements for your region.

Why Choose China Manufacturers?

China has emerged as a global hub for fine chemical manufacturing. By partnering with reputable China manufacturers, businesses can benefit from cost-effectiveness, advanced production capabilities, and a wide range of chemical products. For Alpha-Cyclopentylmandelic Acid, sourcing directly from a Chinese manufacturer can provide a competitive advantage in terms of price and availability.

Finding a Supplier for Alpha-Cyclopentylmandelic Acid

When searching for a supplier, utilize specific keywords like 'Alpha-Cyclopentylmandelic Acid supplier China,' 'buy CAS 427-49-6,' or 'Alpha-Cyclopentylmandelic Acid price.' Engaging directly with manufacturers through their official contact channels, such as those found on industry directories or company websites, is the most effective way to initiate the inquiry and obtain a quote. Remember to clearly state your required quantity, purity, and delivery timeline.

By following these guidelines, procurement professionals can efficiently source high-quality Alpha-Cyclopentylmandelic Acid, ensuring the success of their pharmaceutical development projects. Partnering with a trustworthy manufacturer is the first step towards securing your supply chain and achieving your production goals.