Benzene derivatives form a foundational class of compounds in organic chemistry, with significant applications across various industries, particularly pharmaceuticals. Among these, 3-Hydroxy-4-methoxybenzonitrile (CAS: 52805-46-6) has emerged as a critical intermediate, primarily for its role in the synthesis of Gefitinib, a key drug in targeted cancer therapy. This article will explore the significance of this compound, its chemical properties, and the strategic advantages of sourcing it from specialized manufacturers, especially within China.

3-Hydroxy-4-methoxybenzonitrile, characterized by its chemical formula C8H7NO2 and a molecular weight of 149.15, is typically supplied as a white solid with a high purity profile, often exceeding 98%. Its structure features a benzonitrile core functionalized with hydroxyl and methoxy groups, which are crucial for its reactivity in complex synthetic pathways. The primary application of this compound is in the multi-step synthesis of Gefitinib, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. The precise chemical transformations involving this intermediate are vital for achieving the desired structure and efficacy of the final drug product.

For procurement professionals and R&D scientists in the pharmaceutical sector, sourcing such intermediates requires careful consideration. Factors like purity, consistent quality, reliable supply, and competitive pricing are paramount. China has become a global leader in the production of fine chemicals and pharmaceutical intermediates, offering a compelling ecosystem for sourcing. Manufacturers in China leverage economies of scale and advanced technology to provide high-quality compounds like 3-Hydroxy-4-methoxybenzonitrile at attractive price points. This makes them an ideal partner for companies looking to optimize their procurement strategies.

NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated manufacturer and supplier focused on providing high-quality intermediates to the global pharmaceutical market. We understand the critical importance of compounds like 3-Hydroxy-4-methoxybenzonitrile and are committed to meeting the rigorous standards of our clients. We encourage potential buyers to contact us for detailed product information, quotations, and to discuss custom synthesis needs. Partnering with us ensures access to a reliable supply of this vital benzene derivative.

The ongoing advancements in pharmaceutical research and development underscore the continued importance of specialized chemical intermediates. 3-Hydroxy-4-methoxybenzonitrile is a prime example of a compound that plays a pivotal role in bringing advanced therapies to market. We are dedicated to being your trusted source for this essential material.