Sourcing Boc-His-OH (CAS 20866-46-0): A Guide for Peptide Researchers and Manufacturers
The journey of peptide synthesis, from conceptualization to final product, relies heavily on the quality and availability of its building blocks. N-alpha, N-im-bis-Boc-L-histidine, identified by its CAS number 20866-46-0, is a prime example of such a critical component. As a protected form of histidine, it is indispensable for researchers aiming to synthesize peptides with accuracy and high yield. For those seeking to buy Boc-His(Boc)-OH, understanding the market and supplier landscape is crucial for success.
The inherent reactivity of histidine, particularly its imidazole side chain, necessitates robust protection strategies during peptide synthesis. The Boc (tert-butoxycarbonyl) groups in Boc-His(Boc)-OH serve this purpose effectively by masking both the alpha-amino and the imidazole nitrogen. This dual protection ensures that the histidine residue is incorporated into the peptide chain precisely as intended, without participating in unintended reactions like acylation or alkylation. This level of control is fundamental for producing pure peptides, whether for therapeutic applications, diagnostic tools, or fundamental research. Therefore, securing a reliable supply of this specific protected histidine derivative is a key consideration for any peptide synthesis endeavor.
When exploring where to find high-quality Boc-His-OH, potential buyers often consider factors such as product purity, packaging options, and pricing. The cost of Boc-His(Boc)-OH can vary based on purity levels, order volume, and the supplier's location and reputation. Manufacturers specializing in peptide synthesis reagents and pharmaceutical intermediates, such as NINGBO INNO PHARMCHEM CO.,LTD., play a vital role in ensuring the availability of this compound. By offering meticulously synthesized and purified Boc-His-OH, these companies empower scientists to push the boundaries of peptide research and drug development. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing researchers with the essential tools they need, including this vital protected amino acid.
In conclusion, N-alpha, N-im-bis-Boc-L-histidine (CAS 20866-46-0) is more than just a chemical; it is an enabler of complex peptide synthesis. Its availability from reputable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensures that the scientific community has access to the high-quality materials required to advance peptide-based technologies and therapies.
Perspectives & Insights
Nano Explorer 01
“The cost of Boc-His(Boc)-OH can vary based on purity levels, order volume, and the supplier's location and reputation.”
Data Catalyst One
“Manufacturers specializing in peptide synthesis reagents and pharmaceutical intermediates, such as NINGBO INNO PHARMCHEM CO.”
Chem Thinker Labs
“By offering meticulously synthesized and purified Boc-His-OH, these companies empower scientists to push the boundaries of peptide research and drug development.”