For procurement managers in the pharmaceutical sector, sourcing high-quality intermediates is paramount. N-(tert-Butoxycarbonyl)-L-phenylalanine, commonly known as Boc-L-Phenylalanine (CAS 13734-34-4), is one such critical compound. This article provides a comprehensive guide for buyers looking to purchase this essential amino acid derivative, focusing on reliable manufacturers and suppliers, particularly those based in China.

Boc-L-Phenylalanine is a protected amino acid widely used in peptide synthesis. Its tert-butyloxycarbonyl (Boc) protecting group allows for controlled coupling reactions, making it indispensable in the development of therapeutic peptides and complex organic molecules. Understanding the specifications, purity requirements, and supply chain reliability is crucial for any successful procurement process.

Why is Boc-L-Phenylalanine Important?

The primary utility of Boc-L-Phenylalanine lies in its role as a building block for peptides. Peptides are increasingly important in drug discovery, with applications ranging from metabolic disorder treatments to advanced therapeutics. The Boc protecting group offers stability during synthesis while being easily removable under specific chemical conditions, ensuring the integrity of the final peptide sequence.

Key Considerations When Sourcing Boc-L-Phenylalanine

When you decide to buy Boc-L-Phenylalanine, several factors should be at the forefront of your mind:

  • Purity Levels: Pharmaceutical applications demand high purity, typically exceeding 98%. Certificates of Analysis (CoA) should detail impurity profiles and assay results.
  • CAS Number Verification: Always confirm the CAS number is indeed 13734-34-4 to ensure you are procuring the correct isomer.
  • Supplier Reputation: Partner with established manufacturers and suppliers with a proven track record in the pharmaceutical intermediates market. Look for companies with certifications and positive client testimonials.
  • Production Capacity and Lead Times: Ensure the supplier can meet your required volumes and deliver within your project timelines. Enquiring about price for bulk orders is also advisable.
  • Regulatory Compliance: For certain markets, compliance with GMP (Good Manufacturing Practice) or other regulatory standards may be necessary.

Finding Reliable Manufacturers and Suppliers in China

China has emerged as a global hub for the production of fine chemicals and pharmaceutical intermediates. Several reputable Chinese manufacturers and suppliers offer Boc-L-Phenylalanine. When reaching out, be prepared to discuss your specific needs, including quantity, desired purity, and delivery location. Requesting samples for in-house quality testing is a standard practice. Many companies will be happy to provide a quote upon inquiry.

By thoroughly vetting potential partners and understanding your product requirements, you can secure a consistent and high-quality supply of Boc-L-Phenylalanine, enabling the successful advancement of your pharmaceutical research and development projects. Purchasing from a reliable source minimizes risks and ensures efficiency.