For pharmaceutical manufacturers, the reliable sourcing of high-quality chemical intermediates is paramount to the success of drug development and production. One such critical intermediate is tert-Butyl N-(2-mercaptoethyl)carbamate, also known by its CAS number 67385-09-5. This compound, a Boc-protected thiol, plays a significant role in various synthetic pathways, particularly in the creation of complex organic molecules and novel drug candidates. Understanding its properties and the benefits of sourcing from reputable manufacturers in China can significantly streamline procurement processes.

Why is tert-Butyl N-(2-mercaptoethyl)carbamate Important in Pharma?

The tert-butyl carbamate (Boc) protecting group is widely used in organic synthesis due to its stability under many reaction conditions and its ease of removal under mild acidic conditions. The presence of a thiol group (-SH) in tert-Butyl N-(2-mercaptoethyl)carbamate makes it a versatile nucleophile and a valuable synthon for introducing sulfur-containing functionalities into molecules. This is particularly relevant in pharmaceutical chemistry, where sulfur atoms are often integral to the biological activity of drugs. For instance, it can be employed in the synthesis of peptides, heterocycles, and other complex pharmaceutical intermediates where precise functional group manipulation is required.

Key Considerations for Procurement Managers

When sourcing CAS 67385-09-5 for pharmaceutical manufacturing, procurement managers must prioritize several factors: purity, consistency, scalability, and regulatory compliance. A purity level of NLT 98% is typically a baseline requirement to avoid unwanted side reactions and ensure the quality of the final active pharmaceutical ingredient (API). Consistency between batches is also crucial for maintaining reproducible manufacturing processes. Furthermore, the ability of a supplier to scale up production from laboratory to commercial quantities without compromising quality is essential.

Finding Reliable Suppliers in China

China has emerged as a global hub for chemical manufacturing, offering a wide array of intermediates at competitive prices. For procurement managers looking to buy tert-Butyl N-(2-mercaptoethyl)carbamate, identifying reliable Chinese manufacturers is key. Look for suppliers with established quality management systems, such as ISO certifications, and a proven track record in supplying the pharmaceutical industry. Companies that provide detailed technical data sheets, Certificates of Analysis (CoA), and responsive customer service are generally preferred. Engaging with these suppliers early in the development process can help secure a stable and cost-effective supply chain for this vital intermediate.

Getting a Quote and Exploring Options

To secure your supply of high-purity CAS 67385-09-5, it is advisable to directly contact manufacturers and suppliers. Requesting a quote will allow you to compare pricing and terms from different vendors. Many Chinese chemical manufacturers offer competitive pricing for bulk purchases, making them an attractive option for pharmaceutical companies looking to optimize their procurement costs. By carefully evaluating potential suppliers and their offerings, pharmaceutical manufacturers can ensure they obtain the necessary intermediates to advance their research and production efficiently.