In the fast-paced world of pharmaceutical research and development, the availability of reliable, high-quality chemical building blocks is essential. For scientists and procurement specialists, identifying trusted sources for compounds like (S)-2-(FMOC-amino)-3-(2,2-dimethylbenzo[d][1,3]dioxol-5-yl)propanoic acid, known by its CAS number 852288-18-7 and often abbreviated as Fmoc-Dopa(acetonide)-OH, is a primary objective. This article provides a guide for buyers looking to purchase this critical intermediate, focusing on its applications and how to navigate the sourcing landscape.

Understanding Fmoc-Dopa(acetonide)-OH

Fmoc-Dopa(acetonide)-OH is a derivative of the amino acid DOPA, strategically modified for use in complex chemical syntheses. The FMOC protecting group on the amine function is standard for peptide synthesis, allowing for controlled sequential addition of amino acids. The acetonide protection of the catechol structure enhances stability and simplifies handling during synthesis procedures. Typically appearing as a white to light brown powder, its specified purity of ≥97% is a key indicator of its suitability for demanding research applications, including drug discovery and the synthesis of therapeutic peptides. For any scientist or procurement manager needing to buy this compound, understanding its CAS number (852288-18-7) is the first step in accurate sourcing.

Applications Driving Demand

The demand for Fmoc-Dopa(acetonide)-OH is driven by its critical role in several areas of chemical and pharmaceutical research:

  • Peptide Synthesis: It is a vital component for building peptides with modified structures, enhancing their therapeutic potential, stability, or interaction with biological targets.
  • Drug Discovery: Researchers utilize this intermediate to synthesize novel drug candidates, incorporating its unique chemical features to explore new therapeutic avenues.
  • Biotechnology: It serves as a building block for creating specialized molecules used in various biotechnological applications.

When you need to buy Fmoc-Dopa(acetonide)-OH, ensuring you get a product of the highest quality is paramount for the success of your experiments and development projects.

Finding Reliable Manufacturers and Suppliers

Sourcing chemical intermediates like Fmoc-Dopa(acetonide)-OH often involves looking towards established manufacturing hubs. China, in particular, has a robust chemical industry capable of producing high-purity compounds at competitive price points. When selecting a supplier:

  • Verify Purity and Quality: Always prioritize suppliers who clearly state a purity of ≥97% and provide a comprehensive Certificate of Analysis (CoA) with each order. This document is essential for validating the material's suitability.
  • Check Manufacturer Reputation: Opt for manufacturers with a solid track record in producing fine chemicals and pharmaceutical intermediates. Look for companies that demonstrate strong quality control systems.
  • Evaluate Supply Chain Stability: Ensure the supplier has consistent production capacity and reliable logistics to meet your needs, whether for small research quantities or larger development-scale orders.
  • Seek Competitive Pricing: Engage with manufacturers to obtain quotes, especially for bulk purchases, to ensure cost-effectiveness without compromising on quality.

By focusing on these aspects, procurement professionals can effectively buy Fmoc-Dopa(acetonide)-OH and ensure their research and development projects are supported by high-quality, reliably sourced chemical intermediates.