For researchers and procurement managers in the pharmaceutical and fine chemical industries, sourcing high-quality Chloromethyl Pivalate (CAS 18997-19-8) is paramount. This versatile compound serves as a crucial intermediate in numerous synthetic pathways, particularly in the development of active pharmaceutical ingredients (APIs) and prodrugs. Understanding the nuances of its applications and procurement can significantly impact project success and cost-effectiveness.

Chloromethyl Pivalate is widely recognized for its utility in the N-protection of amines. This chemical transformation is fundamental in multi-step organic synthesis, preventing unwanted side reactions and allowing for controlled manipulation of complex molecules. When considering how to buy this reagent, it's essential to look for suppliers who can guarantee a consistent purity level, as even minor impurities can derail sensitive reactions. For those involved in prodrug development, Chloromethyl Pivalate is instrumental in forming pivaloyloxy methyl esters, a strategy often employed to improve the solubility and bioavailability of certain drugs, such as ofloxacin.

Beyond these specific applications, Chloromethyl Pivalate is a valuable tool in general organic synthesis, including the creation of isoindoline-annulated structures and in continuous-flow organic synthesis. Its reactivity makes it a versatile building block. When searching for a manufacturer, especially one based in China, it’s important to vet their production capabilities and quality control processes. For instance, NINGBO INNO PHARMCHEM CO.,LTD. focuses on delivering high-purity chemical intermediates, making us a reliable source for your bulk purchase needs.

The price of Chloromethyl Pivalate can vary depending on the quantity, purity, and supplier. For research purposes, smaller quantities might be sufficient, while large-scale manufacturing requires bulk orders. Engaging directly with manufacturers or their authorized distributors can often lead to better pricing and lead times. When requesting a quote, be sure to specify your exact requirements, including CAS number (18997-19-8) and desired purity. This ensures you receive an accurate quotation and product that meets your technical specifications. Ultimately, choosing a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures you receive a dependable product backed by responsive customer service, allowing your research and development efforts to proceed smoothly.