For procurement managers and research scientists in the chemical and pharmaceutical industries, sourcing reliable intermediates is paramount. Dihydrofuran-3(2H)-one (CAS 22929-52-8), also known by synonyms like Oxolan-3-one or Tetrahydrofuran-3-one, stands out as a critical building block in organic synthesis. Understanding its properties, applications, and where to buy it can significantly streamline your procurement process.

Dihydrofuran-3(2H)-one is a colorless to yellow liquid, characterized by a boiling point of 68°C at 60mmHg. Its molecular formula C4H6O2 and molecular weight of 86.09 highlight its suitability as a fine chemical intermediate. The primary utility of this compound lies in its role as a reagent in the preparation of dihydropteridinones, which are recognized as orally active Polo-like kinase-2 (Plk-2) inhibitors. This makes it an indispensable component in the early stages of drug discovery and development.

When looking to purchase Dihydrofuran-3(2H)-one, identifying reputable manufacturers and suppliers is key. China has emerged as a significant hub for fine chemical production, offering competitive pricing and a broad supply base. For businesses seeking to buy Dihydrofuran-3(2H)-one, conducting thorough supplier research is essential. Look for manufacturers who can provide a certificate of analysis (CoA) detailing purity (often reported as ≥98.0% by GC), and ensure they have robust quality control measures in place.

The synthesis of Dihydrofuran-3(2H)-one itself typically involves the oxidation of 3-hydroxytetrahydrofuran. Understanding the manufacturing process can provide insights into potential impurities and quality variations. As a buyer, always inquire about the production scale, lead times, and packaging options available from your potential suppliers. Competitive pricing for Dihydrofuran-3(2H)-one is often influenced by order volume and purity specifications.

For those involved in pharmaceutical intermediate sourcing, understanding the long-tail keywords that potential customers use can be beneficial. Phrases like 'buy dihydrofuran-3(2h)-one', 'dihydrofuran-3(2h)-one supplier China', 'CAS 22929-52-8 manufacturer', or 'oxolan-3-one for sale' are common search queries. Establishing a direct relationship with a trusted manufacturer can ensure a stable supply chain and facilitate custom synthesis requirements, potentially leading to better pricing and quicker delivery times. For your next project requiring this vital chemical intermediate, consider partnering with experienced Chinese manufacturers for your Dihydrofuran-3(2H)-one needs.