For pharmaceutical manufacturers and research institutions, the reliable sourcing of high-quality chemical intermediates is paramount. Ethyl 7-chloro-2-oxoheptanoate (CAS: 78834-75-0) is one such critical compound, primarily known for its indispensable role in the synthesis of Cilastatin. This guide provides essential information for procuring this vital ingredient.

Ethyl 7-chloro-2-oxoheptanoate is a key precursor in the multi-step synthesis of Cilastatin, an enzyme inhibitor that protects Imipenem, a powerful antibiotic, from degradation. The combination of Imipenem and Cilastatin is widely used to treat serious bacterial infections, making the consistent supply of this intermediate crucial for global healthcare. Understanding the requirements for the cilastatin sodium synthesis process ensures that the correct specifications for Ethyl 7-chloro-2-oxoheptanoate are met, typically requiring a purity of 98.0% or higher as determined by Gas Chromatography (GC).

When looking to buy Ethyl 7-chloro-2-oxoheptanoate, it is essential to partner with reputable suppliers who prioritize quality control and offer comprehensive documentation. Key factors to consider include the supplier's manufacturing capabilities, adherence to Good Manufacturing Practices (GMP), and the availability of Certificates of Analysis (CoA) that detail product purity, physical properties, and impurity profiles. The chemical properties of ethyl 7-chloro-2-oxoheptanoate, such as its clear yellow liquid appearance and specific gravity, should also be verifiable through the provided documentation.

The market for pharmaceutical intermediates is competitive, with numerous manufacturers and suppliers available. However, for critical applications like the synthesis of cilastatin intermediate, selecting a supplier with a proven track record is vital. Companies like NINGBO INNO PHARMCHEM CO.,LTD. specialize in providing high-purity pharmaceutical chemicals, offering tailored solutions for various production scales. Their commitment to stringent quality assurance processes ensures that clients receive products that meet exacting standards.

The process of researching and selecting a supplier often involves reviewing their product catalog, checking customer testimonials, and ensuring they can meet specific volume requirements. Whether for early-stage research or large-scale manufacturing, the consistent quality of Ethyl 7-chloro-2-oxoheptanoate directly impacts the efficacy and safety of the final pharmaceutical products. Therefore, due diligence in the procurement process is a non-negotiable aspect of pharmaceutical development.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting the pharmaceutical industry by providing essential, high-quality intermediates. We understand the critical nature of compounds like Ethyl 7-chloro-2-oxoheptanoate and are committed to being a reliable partner for your synthesis needs.