Sourcing High-Quality Fmoc-D-2-Chlorophenylalanine: A Guide for Researchers
For researchers engaged in advanced peptide synthesis and pharmaceutical development, obtaining high-quality intermediates is a non-negotiable requirement. Fmoc-D-2-Chlorophenylalanine, identified by CAS number 205526-22-3, is one such critical compound. This article serves as a guide for scientists and procurement managers looking to source this valuable amino acid derivative effectively, highlighting its applications and the benefits of choosing a reliable supplier.
Fmoc-D-2-Chlorophenylalanine is a protected non-proteinogenic amino acid. The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a robust protecting group for the amine function, enabling its use in Fmoc-based solid-phase peptide synthesis (SPPS). The inclusion of a chlorine atom on the phenyl ring of D-phenylalanine imparts unique properties that can alter peptide structure, stability, and biological interactions. This makes it a valuable tool for researchers aiming to develop novel peptides with specific functionalities, often referred to as custom peptide synthesis with chlorinated amino acids.
The primary applications of Fmoc-D-2-Chlorophenylalanine span several key areas within chemical and biological research. In peptide synthesis, it allows for the introduction of a halogenated aromatic side chain, which can influence peptide folding, receptor binding affinity, and resistance to enzymatic degradation. This is particularly important when developing peptide-based therapeutics or probes for biochemical assays.
In drug development, researchers often seek to buy Fmoc-D-2-Chlorophenylalanine to explore novel molecular entities. The chlorinated phenyl ring can modulate electronic properties and lipophilicity, which are key parameters in optimizing drug candidates for efficacy and pharmacokinetic profiles. As a direct Fmoc-D-2-Chlorophenylalanine supplier China, we provide this compound with stringent quality controls, ensuring that researchers receive material of high purity (>97%) for their demanding applications. Understanding the CAS 205526-22-3 price is crucial for efficient resource allocation in R&D projects.
Furthermore, this compound is instrumental in bioconjugation strategies, where peptides are linked to other molecules to create targeted drug delivery systems or diagnostic tools. The stability and reactivity offered by the chlorinated side chain can be leveraged to enhance the performance of these conjugates.
When sourcing Fmoc-D-2-Chlorophenylalanine, several factors should be considered: purity, consistency, availability, and supplier reliability. We pride ourselves on being a trusted manufacturer and supplier, offering competitive pricing and technical support. Our commitment to quality assurance means that every batch of Fmoc-D-2-Chlorophenylalanine meets rigorous specifications, providing researchers with the confidence they need to advance their projects. Contact us to learn more about purchasing options and to secure a consistent supply of this essential intermediate for your laboratory.
Perspectives & Insights
Molecule Vision 7
“Fmoc-D-2-Chlorophenylalanine, identified by CAS number 205526-22-3, is one such critical compound.”
Alpha Origin 24
“This article serves as a guide for scientists and procurement managers looking to source this valuable amino acid derivative effectively, highlighting its applications and the benefits of choosing a reliable supplier.”
Future Analyst X
“The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a robust protecting group for the amine function, enabling its use in Fmoc-based solid-phase peptide synthesis (SPPS).”